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Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody
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Catalog No. TMAC-00536
Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CAMKII beta/gamma/delta (Thr287). Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody can be used in IF,WB,IHC,ELISA.
Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody
Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody
😃Good
Catalog No. TMAC-00536
Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CAMKII beta/gamma/delta (Thr287). Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody can be used in IF,WB,IHC,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $318 | 7-10 days |
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Chemical Properties
| Description | Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CAMKII beta/gamma/delta (Thr287). Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody can be used in IF,WB,IHC,ELISA. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Threonine 287 (Q-E-T(p)-V-E) derived from Human CaMK2- beta/ gamma/ delta |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 50 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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