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Pyrimethanil

Name: Pyrimethanil
Brand: TargetMol
SKU: T37071
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T37071Cas No. 53112-28-0

Pyrimethanil is a strobilurin fungicide belonging to the anilinopyrimidine class. Pyrimethanil is a broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops. Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea.

Pyrimethanil

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Purity: 99.86%

Catalog No. T37071Cas No. 53112-28-0

Pack Size	Price	USA Warehouse	Global Warehouse
100 mg	$33	In Stock	-
500 mg	$80	In Stock	-
1 g	$116	Backorder	Backorder
1 mL x 10 mM (in DMSO)	$30	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.86%

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COA LCMS

Product Introduction

Bioactivity

Description	Pyrimethanil is a strobilurin fungicide belonging to the anilinopyrimidine class. Pyrimethanil is a broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops. Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea.
Targets&IC50	Cellulase:2.5 μM, Polygalacturonase:2.5 μM, Proteinase:2.5 μM, Laccase:1.0 μM
In vitro	Pyrimethanil(3 days) decreased polygalacturonase, cellulase, proteinase and laccase activities. Pyrimethanil resulted in 50% reduction (IC50) in total enzyme activities such as polygalacturonase, cellulase and proteinase(IC50 = approximately 2.5 μM), and laccase(IC50 = 1.0 μM)[3].

Chemical Properties

Molecular Weight	199.25
Formula	C₁₂H₁₃N₃
Cas No.	53112-28-0
Smiles	CC1=CC(C)=NC(NC2=CC=CC=C2)=N1
Relative Density.	1.15

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (301.13 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2.5 mg/mL (12.55 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.0188 mL	25.0941 mL	50.1882 mL	250.9410 mL
5 mM	1.0038 mL	5.0188 mL	10.0376 mL	50.1882 mL
10 mM	0.5019 mL	2.5094 mL	5.0188 mL	25.0941 mL
20 mM	0.2509 mL	1.2547 mL	2.5094 mL	12.5471 mL
50 mM	0.1004 mL	0.5019 mL	1.0038 mL	5.0188 mL
100 mM	0.0502 mL	0.2509 mL	0.5019 mL	2.5094 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc