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Anti-C-MPL Antibody (1H828)

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Catalog No. TMAC-02642

Anti-C-MPL Antibody (1H828) is a Mouse antibody targeting C-MPL. Anti-C-MPL Antibody (1H828) can be used in WB,FCM.

Anti-C-MPL Antibody (1H828)

Anti-C-MPL Antibody (1H828)

😃Good
Catalog No. TMAC-02642
Anti-C-MPL Antibody (1H828) is a Mouse antibody targeting C-MPL. Anti-C-MPL Antibody (1H828) can be used in WB,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4287-10 days
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
Anti-C-MPL Antibody (1H828) is a Mouse antibody targeting C-MPL. Anti-C-MPL Antibody (1H828) can be used in WB,FCM.
Reactivity
Human
Application
Recommended Dose
WB: 1:500-1000; FCM: 1:100-200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
Research BackgroundThrombopoietin was shown to be the major regulator of megakaryocytopoiesis and platelet formation. The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs . TPO-R deficient mice were severely thrombocytopenic, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases, as well as the STAT family, the MAPK family, the adaptor protein Shc and the receptors themselves become tyrosine phosphorylated.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 71 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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