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Anti-CDCP1 Antibody (1L606)

😃Good
Catalog No. TMAY-03551
Alias TRASK, SIMA135, CUB domain containing protein 1, CD318

Anti-CDCP1 Antibody (1L606) is a Rabbit antibody targeting CDCP1. Anti-CDCP1 Antibody (1L606) can be used in ELISA.

Anti-CDCP1 Antibody (1L606)

Anti-CDCP1 Antibody (1L606)

😃Good
Catalog No. TMAY-03551Alias TRASK, SIMA135, CUB domain containing protein 1, CD318
Anti-CDCP1 Antibody (1L606) is a Rabbit antibody targeting CDCP1. Anti-CDCP1 Antibody (1L606) can be used in ELISA.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-CDCP1 Antibody (1L606) is a Rabbit antibody targeting CDCP1. Anti-CDCP1 Antibody (1L606) can be used in ELISA.
AliasTRASK, SIMA135, CUB domain containing protein 1, CD318
Ig Type
Monoclonal Rabbit IgG
Clone
1L606
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse CDCP1 (rM CDCP1; TMPY-02901; Q5U462; Met1-Leu666).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease ST14/MT-SP1. It also interacts with SRC and PRKCG/protein kinase C gamma. CDCP1 is taken as a key regulator of EGF/EGFR-induced cell migration. It has been shown that signaling via EGF/EGFR induces migration of ovarian cancer Caov3 and OVCA420 cells with concomitant up-regulation of CDCP1 mRNA and protein. Consistent with a role in cell migration CDCP1 relocates from cell-cell junctions to punctate structures on filopodia after activation of EGFR. It may be involved in cell adhesion and cell matrix association. It also may play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. It has been taken as a novel marker for leukemia diagnosis and immature hematopoietic stem cell subsets.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse CDCP1 Protein (TMPY-02901)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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