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Anti-CDCP1 Antibody (1L606)
😃Good
Catalog No. TMAY-03551
Alias TRASK, SIMA135, CUB domain containing protein 1, CD318
Anti-CDCP1 Antibody (1L606) is a Rabbit antibody targeting CDCP1. Anti-CDCP1 Antibody (1L606) can be used in ELISA.
Anti-CDCP1 Antibody (1L606)
Anti-CDCP1 Antibody (1L606)
😃Good
Catalog No. TMAY-03551Alias TRASK, SIMA135, CUB domain containing protein 1, CD318
Anti-CDCP1 Antibody (1L606) is a Rabbit antibody targeting CDCP1. Anti-CDCP1 Antibody (1L606) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Mouse |
| Alias | TRASK, SIMA135, CUB domain containing protein 1, CD318 |
| Ig Type | Rabbit IgG |
| Clone | 1L606 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CDCP1 (rM CDCP1; TMPY-02901; Q5U462; Met1-Leu666). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease ST14/MT-SP1. It also interacts with SRC and PRKCG/protein kinase C gamma. CDCP1 is taken as a key regulator of EGF/EGFR-induced cell migration. It has been shown that signaling via EGF/EGFR induces migration of ovarian cancer Caov3 and OVCA420 cells with concomitant up-regulation of CDCP1 mRNA and protein. Consistent with a role in cell migration CDCP1 relocates from cell-cell junctions to punctate structures on filopodia after activation of EGFR. It may be involved in cell adhesion and cell matrix association. It also may play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. It has been taken as a novel marker for leukemia diagnosis and immature hematopoietic stem cell subsets. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse CDCP1 Protein (TMPY-02901) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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