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ULBP-2 Protein, Human, Recombinant (hFc)

(Synonyms: UNQ463 / PRO791, UL16 binding protein 2, RAET1H, NKG2DL2, N2DL2, ALCAN-α, ALCAN-alpha) Copy Product Info

Synonyms: UNQ463 / PRO791, UL16 binding protein 2, RAET1H, NKG2DL2, N2DL2, ALCAN-α, ALCAN-alpha

Catalog No. TMPY-02334 Copy Product Info
ULBP-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.40 kDa and the accession number is Q9BZM5.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$587-10 days7-10 days
10 µg$937-10 days7-10 days
20 µg$1527-10 days7-10 days
50 µg$2987-10 days7-10 days
100 µg$5777-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Human ULBP2, hFc Tag captured on CM5 Chip via Protein A can bind Human NKG2D, His Tag with an affinity constant of 62.42 nM as determined in SPR assay (Biacore T200).
Description
ULBP-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.40 kDa and the accession number is Q9BZM5.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberQ9BZM5
ConstructionGly26-Ser216
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsUNQ463 / PRO791, UL16 binding protein 2, RAET1H, NKG2DL2, N2DL2, ALCAN-α, ALCAN-alpha
Research Background
ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.
Chemical Properties
Molecular Weight48.40 kDa (Predicted); 55-65 kDa (Due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: ULBP-2 Protein, Human, Recombinant (hFc) chemical structure | ULBP-2 Protein, Human, Recombinant (hFc) molecular weight