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ULBP-2 Protein, Human, Recombinant (hFc)

TargetMol | SPR
Catalog No. TMPY-02334

ULBP-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.40 kDa and the accession number is Q9BZM5.

ULBP-2 Protein, Human, Recombinant (hFc)

ULBP-2 Protein, Human, Recombinant (hFc)

TargetMol | SPR
Catalog No. TMPY-02334
ULBP-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.40 kDa and the accession number is Q9BZM5.
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100 μg$5777-10 days
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Product Information

Biological Activity
Human ULBP2, hFc Tag captured on CM5 Chip via Protein A can bind Human NKG2D, His Tag with an affinity constant of 62.42 nM as determined in SPR assay (Biacore T200).
Description
ULBP-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.40 kDa and the accession number is Q9BZM5.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberQ9BZM5
Synonyms
UNQ463 / PRO791,UL16 binding protein 2,RAET1H,NKG2DL2,N2DL2,ALCAN-α,ALCAN-alpha
Construction
Gly26-Ser216
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight48.40 kDa (Predicted); 55-65 kDa (Due to glycosylation)
EndotoxinLess than 1EU per μg by the LAL method.
FormulationLyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.

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Please read the User Guide of Recombinant Proteins for more specific information.

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