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CDDO-2P-Im

Name: CDDO-2P-Im
Brand: TargetMol
SKU: T13602
Price: 98 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T13602Cas No. 1883650-96-1

Alias CDDO-2-P-Im

CDDO-2P-Im shows chemopreventive effect and reduces the size and severity of the lung tumors in the mouse lung cancer model.

CDDO-2P-Im

🥰Excellent

Purity: 99.54%

Catalog No. T13602Alias CDDO-2-P-ImCas No. 1883650-96-1

CDDO-2P-Im shows chemopreventive effect and reduces the size and severity of the lung tumors in the mouse lung cancer model.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$98	In Stock	In Stock
5 mg	$228	In Stock	In Stock
10 mg	$372	In Stock	In Stock
25 mg	$615	In Stock	In Stock
50 mg	$869	In Stock	In Stock
100 mg	$1,170	In Stock	In Stock
200 mg	$1,570	-	In Stock
1 mL x 10 mM (in DMSO)	$313	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.54%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	CDDO-2P-Im shows chemopreventive effect and reduces the size and severity of the lung tumors in the mouse lung cancer model.
In vitro	In RAW264.7 cells, CDDO-2P-Im suppresses NO production (IC50: 5.8 nM). CDDO-2P-Im (100 nM) induces differentiation of U937 cells[1].
In vivo	CDDO-2P-Im significantly elevates heme oxygenase-1 and quinone reductase mRNA and protein levels. In A/J mice, CDDO-2P-Im (50-200 mg/kg) decreases the number, size, and severity of tumors[1].
Synonyms	CDDO-2-P-Im

Chemical Properties

Molecular Weight	618.81
Formula	C₃₉H₄₆N₄O₃
Cas No.	1883650-96-1
Smiles	[H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)[C@]2([H])C(=O)C=C2[C@@]3(C)C=C(C#N)C(=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)n1cnc(c1)-c1ccccn1
Relative Density.	1.25 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 112.5 mg/mL (181.8 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 3.3 mg/mL (5.33 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6160 mL	8.0800 mL	16.1600 mL	80.8002 mL
5 mM	0.3232 mL	1.6160 mL	3.2320 mL	16.1600 mL
10 mM	0.1616 mL	0.8080 mL	1.6160 mL	8.0800 mL
20 mM	0.0808 mL	0.4040 mL	0.8080 mL	4.0400 mL
50 mM	0.0323 mL	0.1616 mL	0.3232 mL	1.6160 mL
100 mM	0.0162 mL	0.0808 mL	0.1616 mL	0.8080 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc