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Amp579 TFA

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Catalog No. T67972L
Alias Amp579 TFA(213453-89-5 Free base)

Amp579 TFA is a novel adenosine A1/A2a receptor agonist that induces acute and delayed preconditioning against myocardial shock in vivo.

Amp579 TFA

Amp579 TFA

😃Good
Purity: 97.91%
Catalog No. T67972LAlias Amp579 TFA(213453-89-5 Free base)
Amp579 TFA is a novel adenosine A1/A2a receptor agonist that induces acute and delayed preconditioning against myocardial shock in vivo.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$195-In Stock
5 mg$465-In Stock
10 mg$679-In Stock
25 mg$1,070-In Stock
50 mg$1,430-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:97.91%
ee:99.23%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
Amp579 TFA is a novel adenosine A1/A2a receptor agonist that induces acute and delayed preconditioning against myocardial shock in vivo.
SynonymsAmp579 TFA(213453-89-5 Free base)
Chemical Properties
Molecular Weight592.03
FormulaC24H29ClF3N5O5S
SmilesO[C@H]1[C@@H](C[C@@H]([C@H]1O)C(NCC)=O)N2C3=NC=NC(N[C@H](CC)CC4=C(C=CS4)Cl)=C3C=C2.OC(C(F)(F)F)=O
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (92.9 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6891 mL8.4455 mL16.8910 mL84.4552 mL
5 mM0.3378 mL1.6891 mL3.3782 mL16.8910 mL
10 mM0.1689 mL0.8446 mL1.6891 mL8.4455 mL
20 mM0.0845 mL0.4223 mL0.8446 mL4.2228 mL
50 mM0.0338 mL0.1689 mL0.3378 mL1.6891 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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