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Anti-ASGR2 Antibody (3P650)
😃Good
Catalog No. TMAY-02659
Alias HL-2, HBXBP, CLEC4H2, asialoglycoprotein receptor 2, ASGP-R2, ASGPR2
Anti-ASGR2 Antibody (3P650) is a Rabbit antibody targeting ASGR2. Anti-ASGR2 Antibody (3P650) can be used in ELISA,IHC-P,FCM,ICC/IF.
Anti-ASGR2 Antibody (3P650)
Anti-ASGR2 Antibody (3P650)
😃Good
Catalog No. TMAY-02659Alias HL-2, HBXBP, CLEC4H2, asialoglycoprotein receptor 2, ASGP-R2, ASGPR2
Anti-ASGR2 Antibody (3P650) is a Rabbit antibody targeting ASGR2. Anti-ASGR2 Antibody (3P650) can be used in ELISA,IHC-P,FCM,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-ASGR2 Antibody (3P650) is a Rabbit antibody targeting ASGR2. Anti-ASGR2 Antibody (3P650) can be used in ELISA,IHC-P,FCM,ICC/IF. |
| Alias | HL-2, HBXBP, CLEC4H2, asialoglycoprotein receptor 2, ASGP-R2, ASGPR2 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 3P650 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human ASGR2 in human liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human ASGR2 in human cirrhosis with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 3. Flow cytometric analysis of Human ASGR2 expression on HepG2 cells. Cells were stained with purified anti-Human ASGR2, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. 4. Immunofluorescence staining of ASGR2 in HepG2 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-human ASGR2 monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). |
| Application | ELISA,IHC-P,FCM,ICC/IF |
| Recommended Dose | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500; ICC-IF: 1:20-1:100; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ASGR2 / ASGPR2 (rh ASGR2 / ASGPR2; TMPY-02909; P07307-1; Gln80-Ala311). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | ASGR2 is a subunit of the asialoglycoprotein receptor. Asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively in hepatic parenchymal cells. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. ASGR2 is a glycoprotein. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. ASGR2 is the less abundant minor subunit. |
| Conjucates | Unconjugated |
| Others Formats | PE |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human ASGR2 / ASGPR2 protein (TMPY-02909) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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