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Anti-PRLR Antibody (5U248) is an antibody targeting PRLR. Anti-PRLR Antibody (5U248) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $207 | 7-10 days | |
100 μL | $348 | 7-10 days |
Description | Antibody Type: Recombinant Monoclonal Application: ELISA Reactivity: Human, Mouse |
Alias | prolactin receptor, PRLR, MFAB, hPRLrI, HPRL |
Ig Type | Human IgG2 |
Clone | 5U248 |
Reactivity | Human, Mouse |
Verified Activity | 1. The Binding Activity of Human PRLR with Anti-PRLR recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human PRLR at 2 μg/mL can bind Anti-PRLR recombinant antibody, the EC50 is 126.8-171.9 ng/mL. 2. The Binding Activity of Mouse Prlr with Anti-PRLR recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Prlr at 5 μg/mL can bind Anti-PRLR recombinant antibody, the EC50 is 4.021-8.706 ng/mL. |
Application | ELISA |
Antibody Type | Monoclonal |
Subcellular Localization | Membrane; Single-pass type I membrane protein.; [Isoform 7]: Secreted. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
Research Background | This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human PRLR Protein |
Antigen Species | Human |
Gene ID | 5618 |
Uniprot ID | |
Biology Area | Immunology |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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