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Anti-PRLR Antibody (5U248) is an antibody targeting PRLR. Anti-PRLR Antibody (5U248) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
| Description | Anti-PRLR Antibody (5U248) is an antibody targeting PRLR. Anti-PRLR Antibody (5U248) can be used in ELISA. |
| Synonyms | prolactin receptor, PRLR, MFAB, hPRLrI, HPRL |
| Ig Type | Human IgG2 |
| Clone | 5U248 |
| Reactivity | Human, Mouse |
| Verified Activity | 1. The Binding Activity of Human PRLR with Anti-PRLR recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human PRLR at 2 μg/mL can bind Anti-PRLR recombinant antibody, the EC50 is 126.8-171.9 ng/mL. 2. The Binding Activity of Mouse Prlr with Anti-PRLR recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Prlr at 5 μg/mL can bind Anti-PRLR recombinant antibody, the EC50 is 4.021-8.706 ng/mL. |
| Application | |
| Antibody Type | Monoclonal |
| Subcellular Localization | Membrane; Single-pass type I membrane protein.; [Isoform 7]: Secreted. |
| Tissue Specificity | Expressed in breast, placenta, kidney, liver and pancreas. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human PRLR Protein |
| Antigen Species | Human |
| Gene Name | PRLR |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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