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Anti-Phospho-EGF Receptor (Thr669) Antibody (8Z529)
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Catalog No. TMAY-01717
Alias PIG61, Phospho-EGF Receptor (T669), p-EGF Receptor (Thr669), p-EGF Receptor (T669), NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB, EGF Receptor (pThr669), EGF Receptor (pT669)
Anti-Phospho-EGF Receptor (Thr669) Antibody (8Z529) is a Rabbit antibody targeting Phospho-EGF Receptor (Thr669). Anti-Phospho-EGF Receptor (Thr669) Antibody (8Z529) can be used in WB.
Anti-Phospho-EGF Receptor (Thr669) Antibody (8Z529)
Anti-Phospho-EGF Receptor (Thr669) Antibody (8Z529)
😃Good
Catalog No. TMAY-01717Alias PIG61, Phospho-EGF Receptor (T669), p-EGF Receptor (Thr669), p-EGF Receptor (T669), NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB, EGF Receptor (pThr669), EGF Receptor (pT669)
Anti-Phospho-EGF Receptor (Thr669) Antibody (8Z529) is a Rabbit antibody targeting Phospho-EGF Receptor (Thr669). Anti-Phospho-EGF Receptor (Thr669) Antibody (8Z529) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 20 μL | $80 | 7-10 days | 7-10 days | |
| 100 μL | $235 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Antigen Details
Chemical Properties
| Description | Anti-Phospho-EGF Receptor (Thr669) Antibody (8Z529) is a Rabbit antibody targeting Phospho-EGF Receptor (Thr669). Anti-Phospho-EGF Receptor (Thr669) Antibody (8Z529) can be used in WB. |
| Synonyms | PIG61, Phospho-EGF Receptor (T669), p-EGF Receptor (Thr669), p-EGF Receptor (T669), NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB, EGF Receptor (pThr669), EGF Receptor (pT669) |
| Ig Type | Rabbit IgG |
| Clone | 8Z529 |
| Reactivity | Human;
Predicted to React with:Species predicted to react based on 100% sequence homology: Mouse, Cynomolgus |
| Specificity | Phospho-EGF Receptor (Thr669), which correspond to Phospho-EGF Receptor (Thr693) of P00533-1 in UniProt.
Species predicted to react based on 100% sequence homology: Mouse, Cynomolgus |
| Verified Activity | 1. Western blot analysis of extracts from serum-starved Hela, untreated(line A) or treated with EGF (100ng/mL, 10min; +)(line B), using Phospho-EGF Receptor (Thr669) rabbit monoclonal Antibody at 1:2000 dilution (upper) or Anti-EGF Receptor Antibody, Rabbit Polyclonal at 1:1000 dilution (lower).
2. Western blot analysis of extracts from serum-starved Hela, untreated (line A); treated with EGF (100ng/mL, 10min), without peptide (line B) or antigen-specific phosphopeptide (line C) or antigen-specific peptide (line D) using Phospho-EGF Receptor (Thr669) rabbit monoclonal Antibody at 1:2000 dilution. (Validation Experiment) |
| Application | |
| Recommended Dose | WB: 1:2000-1:20000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the residues around (Thr669) of Human EGF Receptor. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| Research Background | As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: residues around (Thr669) of Human EGF Receptor |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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