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Anti-Phospho-MYC (Thr58, 62) Antibody (3N813) is a Rabbit antibody targeting Phospho-MYC (Thr58, 62). Anti-Phospho-MYC (Thr58, 62) Antibody (3N813) can be used in ICC/IF,IP,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
| Description | Anti-Phospho-MYC (Thr58, 62) Antibody (3N813) is a Rabbit antibody targeting Phospho-MYC (Thr58, 62). Anti-Phospho-MYC (Thr58, 62) Antibody (3N813) can be used in ICC/IF,IP,WB. |
| Synonyms | p-MYC (Thr58, Ser62), p-MYC (T58, S62), MYC (p-Thr58, Ser62), MYC (p-T58, S62) |
| Ig Type | IgG |
| Clone | 3N813 |
| Reactivity | Human,Rat |
| Verified Activity | Western blot analysis of Phospho-c-Myc (T58+S62) on K562 cells lysates using anti-Phospho-c-Myc (T58+S62) antibody at 1/1,000 dilution. |
| Application | |
| Recommended Dose | WB: 1:1000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | c-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease. Myc proteins are nuclear proteins with relatively short half lives. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas. The L-Myc gene has been reported to be amplified and expressed at high level in human small cell lung carcinomas. The presence of three sequence motifs in the c-Myc COOH terminus, including the leucine zipper, the helix-loop-helix and a basic region provided initial evidence for a sequence-specific binding function. A basic region helix-loop-helix leucine zipper motif (bHLH-Zip) protein, designated Max, specifically associates with c-Myc, N-Myc and L-Myc proteins. The Myc-Max complex binds to DNA in a sequence-specific manner under conditions where neither Max nor Myc exhibit appreciable binding. Max can also form heterodimers with at least two additional bHLH-Zip proteins, Mad and Mxi1, and Mad-Max dimers have been shown to repress transcription through interaction with mSin3. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human c-Myc around the phosphorylation site of Thr58 and Ser62 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 49 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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