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Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591)
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Catalog No. TMAY-01521
Alias PIG61, NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB
Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591) is a Rabbit antibody targeting Phospho-EGF Receptor (Tyr1068). Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591) can be used in WB.
Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591)
Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591)
😃Good
Catalog No. TMAY-01521Alias PIG61, NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB
Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591) is a Rabbit antibody targeting Phospho-EGF Receptor (Tyr1068). Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $80 | 7-10 days | |
| 100 μL | $233 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591) is a Rabbit antibody targeting Phospho-EGF Receptor (Tyr1068). Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591) can be used in WB. |
| Alias | PIG61, NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4Z591 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of extracts from serum-starved Hela, untreated (-) or treated with EGF using Phospho-EGF Receptor (Tyr1068) rabbit monoclonal Antibody at 1:2000 dilution (upper), or Anti-EGFR Antibody, Rabbit Polyclonal at 1:2000 dilution (lower). 2. Western blot analysis of extracts from serum-starved Hela, treated with EGF (10 ng/mL, 30 min), using Phospho-EGF Receptor (Tyr1068) Antibody and other brands’ antibodies (company C) at dilution of 1:2000, 1:20000 and 1:200000. (Validation Experiment) 3. Western blot analysis of extracts from serum-starved Hela, untreated (line A); treated with EGF or antigen-specific phosphopeptide (line C) or antigen-specific peptide (line D) using Phospho-EGF Receptor (Tyr1068) rabbit monoclonal Antibody at 1:5000 dilution. (Validation Experiment) 4. Western blot analysis of extracts from serum-starved Hela, untreated (line A); treated with EGF using Phospho-EGF Receptor (Tyr1068) rabbit monoclonal Antibody at 1:5000 dilution. (Validation Experiment) |
| Application | WB |
| Recommended Dose | WB: 1:1000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the residues around Tyr1068 of Human Phospho-EGF Receptor. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| Research Background | As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide corresponding to the residues around Tyr1068 of Human Phospho-EGF Receptor |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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