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Anti-PYCARD Polyclonal Antibody 3
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Catalog No. TMAB-01597
Alias TMS1, Target of methylation-induced silencing 1, PYD and CARD domain-containing protein, PYCARD, hASC, Caspase recruitment domain-containing protein 5, CARD5, ASC, Apoptosis-associated speck-like protein containing a CARD
Anti-PYCARD Polyclonal Antibody 3 is a Rabbit antibody targeting PYCARD. Anti-PYCARD Polyclonal Antibody 3 can be used in WB.
Anti-PYCARD Polyclonal Antibody 3
Anti-PYCARD Polyclonal Antibody 3
😃Good
Catalog No. TMAB-01597Alias TMS1, Target of methylation-induced silencing 1, PYD and CARD domain-containing protein, PYCARD, hASC, Caspase recruitment domain-containing protein 5, CARD5, ASC, Apoptosis-associated speck-like protein containing a CARD
Anti-PYCARD Polyclonal Antibody 3 is a Rabbit antibody targeting PYCARD. Anti-PYCARD Polyclonal Antibody 3 can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $374 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PYCARD Polyclonal Antibody 3 is a Rabbit antibody targeting PYCARD. Anti-PYCARD Polyclonal Antibody 3 can be used in WB. |
| Synonyms | TMS1, Target of methylation-induced silencing 1, PYD and CARD domain-containing protein, PYCARD, hASC, Caspase recruitment domain-containing protein 5, CARD5, ASC, Apoptosis-associated speck-like protein containing a CARD |
| Ig Type | IgG |
| Reactivity | Mouse,Rat |
| Verified Activity | Sample: Lane 1: Mouse LympHnode tissue lysates Lane 2: Mouse Lung tissue lysates Lane 3: Mouse Spleen tissue lysates Lane 4: Rat LympHnode tissue lysates Lane 5: Rat Lung tissue lysates Lane 6: Rat Spleen tissue lysates Primary: Anti-ASC/TMS1 (TMAB-01597) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 22 kDa Observed band size: 24 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Note=Upstream of caspase activation, a redistribution from the cytoplasm to the aggregates occurs. These appear as hollow, perinuclear spherical, ball-like structures. |
| Tissue Specificity | Widely expressed at low levels. Detected in peripheral blood leukocytes, lung, small intestine, spleen, thymus, colon and at lower levels in placenta, liver and kidney. Very low expression in skeletal muscle, heart and brain. Detected in the leukemia cell |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Immunogen | Recombinant Protein: mouse PYCARD protein |
| Antigen Species | Mouse |
| Gene Name | PYCARD |
| Protein Name | Apoptosis-associated speck-like protein containing a CARD |
| Biology Area | Tumor biomarkers,Associated Proteins,CARD Family |
| Function | Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases. |
| Molecular Weight | Theoretical: 22 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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