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C5AR1 Protein, Human, Recombinant (Cell-Free, His)

Catalog No. TMPH-01023
Synonyms: C5a anaphylatoxin chemotactic receptor 1, C5R1, C5a-R, C5a anaphylatoxin chemotactic receptor, C5AR1, C5AR, CD88

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.

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C5AR1 Protein, Human, Recombinant (Cell-Free, His)
Pack Size Availability Price/USD Quantity
20 μg 20 days $ 1,980.00
100 μg 20 days $ 3,230.00
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Biological Description
Technical Params
Product Properties
Description Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.
Species Human
Expression System in vitro E. coli expression system
Tag C-terminal 10xHis-tagged
Accession Number P21730
Synonyms C5a anaphylatoxin chemotactic receptor 1, C5R1, C5a-R, C5a anaphylatoxin chemotactic receptor, C5AR1, C5AR, CD88
Amino Acid MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Construction 1-350 aa
Protein Purity > 90% as determined by SDS-PAGE.
Molecular Weight 40.7 kDa as predicted
Formulation If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.

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Keywords

C5AR1 Protein, Human, Recombinant (Cell-Free, His) C5a anaphylatoxin chemotactic receptor 1 C5R1 C5a-R C5a anaphylatoxin chemotactic receptor C5AR1 C5AR CD88 recombinant recombinant-proteins proteins protein

 

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