Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-CD55/DAF Antibody-HRP (2Y444)
😃Good
Catalog No. TMAY-00256H
Alias GPI-DAF, Daf-GPI, Daf1, Daf, CD55 molecule, decay accelerating factor for complement (Cromer blood group)
Anti-CD55/DAF Antibody-HRP (2Y444) is a HRP-conjugated Mouse antibody targeting CD55/DAF. Anti-CD55/DAF Antibody-HRP (2Y444) can be used in ELISA.
Anti-CD55/DAF Antibody-HRP (2Y444)
Anti-CD55/DAF Antibody-HRP (2Y444)
😃Good
Catalog No. TMAY-00256HAlias GPI-DAF, Daf-GPI, Daf1, Daf, CD55 molecule, decay accelerating factor for complement (Cromer blood group)
Anti-CD55/DAF Antibody-HRP (2Y444) is a HRP-conjugated Mouse antibody targeting CD55/DAF. Anti-CD55/DAF Antibody-HRP (2Y444) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μg | $292 | 7-10 days |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | GPI-DAF, Daf-GPI, Daf1, Daf, CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| Ig Type | Mouse IgG1 |
| Clone | 2Y444 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 0.1-1 μg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD55 / DAF (rh CD55; TMPY-01292; NP_000565.1; Met 1-Ser 353). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It is a major regulator of the alternative and classical pathways of complement activation and is expressed on all serum-exposed cells. CD55 is physiologically acting as an inhibitor of the complement system, but is also broadly expressed in malignant tumours. DAF seems to exert different functions beyond its immunological role such as promotion of tumorigenesis, decrease of complement mediated tumor cell lysis, autocrine loops for cell rescue and evasion of apoptosis, neoangiogenesis, invasiveness, cell motility. It is commonly hijacked by invading pathogens, including many enteroviruses and uropathogenic Escherichia coli, to promote cellular attachment prior to infection. This 70-75 kDa glycoprotein CD55 containing four SCR modules is involved in the regulation of the complement cascade. It inhibits complement activation by suppressing the function of C3/C5 convertases, thereby limiting local generation or deposition of C3a/C5a and membrane attack complex (MAC or C5b-9) production. DAF has been identified as a ligand for an activation-associated, seven-transmembrane lymphocyte receptor, CD97, which is a receptor mediating attachment and infection of several viruses and bacteria. In addition, it has been shown that DAF regulates the interplay between complement and T cell immunity in vivo, and thus may be implicated in immune and tumor biology. |
| Conjucates | HRP |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Protein: Human CD55 protein (TMPY-01292) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
Sci Citations
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Anti-CD55/DAF Antibody-HRP (2Y444) | purchase Anti-CD55/DAF Antibody-HRP (2Y444) | Anti-CD55/DAF Antibody-HRP (2Y444) cost | order Anti-CD55/DAF Antibody-HRP (2Y444)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.