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Anti-RP105/CD180 Antibody (7P240)
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Catalog No. TMAY-03323
Alias RP105, Ly78, LY64, CD180 molecule
Anti-RP105/CD180 Antibody (7P240) is a Rabbit antibody targeting RP105/CD180. Anti-RP105/CD180 Antibody (7P240) can be used in ELISA,IHC-P.
Anti-RP105/CD180 Antibody (7P240)
Anti-RP105/CD180 Antibody (7P240)
😃Good
Catalog No. TMAY-03323Alias RP105, Ly78, LY64, CD180 molecule
Anti-RP105/CD180 Antibody (7P240) is a Rabbit antibody targeting RP105/CD180. Anti-RP105/CD180 Antibody (7P240) can be used in ELISA,IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA, IHC-P Reactivity: Mouse |
| Alias | RP105, Ly78, LY64, CD180 molecule |
| Ig Type | Rabbit IgG |
| Clone | 7P240 |
| Reactivity | Mouse |
| Verified Activity | 1. Immunochemical staining of mouse CD180 in mouse thymus with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of mouse CD180 in mouse spleen with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). |
| Application | ELISA,IHC-P |
| Recommended Dose | ELISA: 1:5000-1:10000; IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD180 / RP105 (rM CD180 / RP105; TMPY-01667; NP_032559.2; Met1-Ser626). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD180, also known as RP105, is a B-cell surface molecule belonging to the family of pathogen receptors, Toll-like receptors (TLR). CD180 has an extracellular leucine-rich repeats and a short cytoplasmic tail. CD180 / RP105 interacts with an extracellular molecule named MD1 and then together form the cell surface receptor complex RP105 / MD1 which induces B-cell activation in humans and mice, leading to proliferation and up-regulation of a costimulatory molecule, B7.2 / CD86. CD180 / RP105 also has a role in LPS response because B cells lacking RP105 show hyporesponsiveness to LPS. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse CD180 / RP105 Protein (TMPY-01667) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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