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Anti-IL-8/CXCL8 Polyclonal Antibody is a Rabbit antibody targeting IL-8/CXCL8. Anti-IL-8/CXCL8 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
| Description | Anti-IL-8/CXCL8 Polyclonal Antibody is a Rabbit antibody targeting IL-8/CXCL8. Anti-IL-8/CXCL8 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB. |
| Synonyms | NAP-1, NAP1, NAF, MONAP, MDNCF, LYNAP, LUCT, LECT, Interleukin-8, IL-8, IL8, GCP-1, GCP1, chemokine (C-X-C motif) ligand 8 |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | Sample: Lane 1: Human MCF-7 cell lysates Lane 2: Human A549 cell lysates Lane 3: Human 293T cell lysates Lane 4: Human K562 cell lysates Primary: Anti-IL-8/CXCL8 (TMAB-00966) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 8/9 kDa Observed band size: 10 kDa ![]() |
| Application | |
| Recommended Dose | IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human IL-8 |
| Antigen Species | Human |
| Gene Name | CXCL8 |
| Gene ID | |
| Protein Name | Interleukin-8 |
| Uniprot ID | |
| Biology Area | SARS Coronavirus,Interleukins,Interleukin,Angiogenic growth factors |
| Function | IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. |
| Molecular Weight | Theoretical: 8/9 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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