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Picrasidine Q
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Catalog No. TN6651Cas No. 101219-61-8
Picrasidine Q is an anticancer natural alkaloid that targets FGFR2, inducing apoptosis and G1 arrest in oesophageal squamous cell carcinoma (ESCC) cells.
Picrasidine Q
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Catalog No. TN6651Cas No. 101219-61-8
Picrasidine Q is an anticancer natural alkaloid that targets FGFR2, inducing apoptosis and G1 arrest in oesophageal squamous cell carcinoma (ESCC) cells.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $422 | Inquiry | Inquiry |
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Appearance:Solid
Color:Yellow
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| Description | Picrasidine Q is an anticancer natural alkaloid that targets FGFR2, inducing apoptosis and G1 arrest in oesophageal squamous cell carcinoma (ESCC) cells. |
| Targets&IC50 | A549 cells:16.2 μg/mL (ED50), MCF7:18.1 μg/mL (ED50) |
| In vitro | Methods: Picrasidine Q (0-60 μM) was used to treat the human esophageal cancer cell lines (including KYSE30, KYSE410, and KYSE450). Cell proliferation was measured by MTT assay; flow cytometry was employed to analyze cell cycle distribution and apoptosis; and changes in related protein expression levels were examined through Western blotting. Results: Picrasidine Q effectively inhibited the proliferation of ESCC cells and significantly induced their apoptosis.[1] |
| Molecular Weight | 266.25 |
| Formula | C15H10N2O3 |
| Cas No. | 101219-61-8 |
| Smiles | O=C1C(OC)=C(O)C2=NC=CC=3C4=CC=CC=C4N1C23 |
| Relative Density. | 1.51 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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