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TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant
(Synonyms: TNFRSF1A, TNFR60, TNF-R55, TNFAR, Soluble Tumor Necrosis Factor type I, p55, CD120a) Copy Product InfoSynonyms: TNFRSF1A, TNFR60, TNF-R55, TNFAR, Soluble Tumor Necrosis Factor type I, p55, CD120a
Catalog No. TMPS-00136 Copy Product Info
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant is expressed in CHO Cells. The accession number is P19438-1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $85 | 7-10 days | 7-10 days | |
| 10 μg | $138 | 7-10 days | 7-10 days | |
| 20 μg | $197 | 7-10 days | 7-10 days | |
| 50 μg | $339 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | ED 50 < 50.0 ng/ml, measured in a cell proliferation assay using 929 cells in the presence of 1.0 ng/ml human TNF-α. |
| Description | TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant is expressed in CHO Cells. The accession number is P19438-1. |
| Species | Human |
| Expression System | CHO Cells |
| Tag | Tag Free |
| Accession Number | P19438-1 |
| Construction | Asp41-Asn202 |
| Protein Purity | > 95% as determined by SDS-PAGE |
| Endotoxin | < 0.2 EU/μg of protein as determined by the LAL method. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | TNFRSF1A, TNFR60, TNF-R55, TNFAR, Soluble Tumor Necrosis Factor type I, p55, CD120a |
| Research Background | TNF Receptor Type I, is also known as TNF R-p55/p60 and TNFRSF1A. It is a type I transmembrane protein member of the TNF receptor superfamily. It is expressed in most cell types. Binding of either TNF-α or TNF-β to TNF-R1 initiates a signal transduction pathway that results in the activation of the transcription factor NF-κB, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells, induce apoptosis. TNF-R1 is essential for proper development of lymph node germinal centers and Peyer’s patches and for combating intracellular pathogens such as Listeria. It is stored in the Golgi and translocates to the cell surface following proinflammatory stimuli. |
| Molecular Weight | 28~35 kDa (Reducing conditions) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant chemical structure | TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant molecular weight
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