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IFNAR1 Protein, Mouse, Recombinant (hFc)

IFNAR1 Protein, Mouse, Recombinant (hFc)
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IFNAR1 Protein, Mouse, Recombinant (hFc)

Catalog No. TMPK-00343
IFNAR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 72.5 kDa and the accession number is P33896.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
100 μg$4657-10 days
500 μg$1,8507-10 days
1 mg$3,1007-10 days
Bulk & Custom
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Biological Description

Biological Information
Mouse IFN alpha/beta R1, hFc Tag immobilized on CM5 Chip can bind Human IFN alpha 1, hFc Tag with an affinity constant of 20.35 nM as determined in SPR assay.
Description
IFNAR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 72.5 kDa and the accession number is P33896.
Species
Mouse
Expression System
HEK293 Cells
TagC-hFc
Accession NumberP33896
Synonyms
AVP,IFNBR,IFN-alpha/β R1,IFNAR,IFN-aR1,IFN-α-REC,IFNbR1,IFN-R-1,CRF2-1,IFN-alpha-REC,IFN-alpha/beta R1,IFRC,IFN-α/β R1,IFN α/β R1,IFNAR1
Construction
Glu27-Thr429
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight72.5 kDa (predicted). Due to glycosylation, the protein migrates to 83-110 kDa based on Tris-Bis PAGE result.
Endotoxin< 1 EU/μg by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice.
Research Background
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits of the different receptor complexes are shared and serve multiple functions.Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords