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IFNAR1 Protein, Mouse, Recombinant (hFc)

(Synonyms: IFRC, IFN-α-REC, IFN-α/β R1, IFN-R-1, IFNbR1, IFNBR, IFN-aR1, IFNAR1, IFNAR, IFN-alpha-REC, IFN-alpha/β R1, IFN-alpha/beta R1, IFN α/β R1, CRF2-1, AVP) Copy Product Info

Synonyms: IFRC, IFN-α-REC, IFN-α/β R1, IFN-R-1, IFNbR1, IFNBR, IFN-aR1, IFNAR1, IFNAR, IFN-alpha-REC, IFN-alpha/β R1, IFN-alpha/beta R1, IFN α/β R1, CRF2-1, AVP

Catalog No. TMPK-00343 Copy Product Info
IFNAR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 72.5 kDa and the accession number is P33896.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$56-In Stock
10 μg$88-In Stock
20 μg$1437-10 days7-10 days
50 μg$2787-10 days7-10 days
100 μg$4657-10 days7-10 days
200 μg$8397-10 days7-10 days
500 μg$1,850-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95% as determined by Bis-Tris PAGE
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Mouse IFN alpha/beta R1, hFc Tag immobilized on CM5 Chip can bind Human IFN alpha 1, hFc Tag with an affinity constant of 20.35 nM as determined in SPR assay.
Description
IFNAR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 72.5 kDa and the accession number is P33896.
Species
Mouse
Expression System
HEK293 Cells
TagC-hFc
Accession NumberP33896
ConstructionGlu27-Thr429
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsIFRC, IFN-α-REC, IFN-α/β R1, IFN-R-1, IFNbR1, IFNBR, IFN-aR1, IFNAR1, IFNAR, IFN-alpha-REC, IFN-alpha/β R1, IFN-alpha/beta R1, IFN α/β R1, CRF2-1, AVP
Research Background
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits of the different receptor complexes are shared and serve multiple functions.Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves.
Chemical Properties
Molecular Weight72.5 kDa (predicted). Due to glycosylation, the protein migrates to 83-110 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: IFNAR1 Protein, Mouse, Recombinant (hFc) chemical structure | IFNAR1 Protein, Mouse, Recombinant (hFc) molecular weight