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Anti-ATP7B Polyclonal Antibody

(Synonyms: WND/140 kDa, WND, Wilson disease associated protein, WD, WC1, tx, Toxic milk, PWD, Cu++ transporting, Cu(2+) transporting, Copper transporting ATPase 2, Copper pump 2, beta polypeptide, ATPase, ATP7B) Copy Product Info
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Synonyms: WND/140 kDa, WND, Wilson disease associated protein, WD, WC1, tx, Toxic milk, PWD, Cu++ transporting, Cu(2+) transporting, Copper transporting ATPase 2, Copper pump 2, beta polypeptide, ATPase, ATP7B

Catalog No. TMAB-00171 Copy Product Info
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Anti-ATP7B Polyclonal Antibody is a Rabbit antibody targeting ATP7B. Anti-ATP7B Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-ATP7B Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ATP7B Polyclonal Antibody is a Rabbit antibody targeting ATP7B. Anti-ATP7B Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
SynonymsWND/140 kDa, WND, Wilson disease associated protein, WD, WC1, tx, Toxic milk, PWD, Cu++ transporting, Cu(2+) transporting, Copper transporting ATPase 2, Copper pump 2, beta polypeptide, ATPase, ATP7B
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Chicken,Pig,Rabbit)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationGolgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Isoform 2: Cytoplasm. WND/140 kDa: Mitochondrion.
Tissue SpecificityMost abundant in liver and kidney and also found in brain. Isoform 2 is expressed in brain but not in liver. The cleaved form WND/140 kDa is found in liver cell lines and other tissues.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ATP7B
Antigen Species
Human
Gene Name
ATP7B
Gene ID
Protein Name
BTLA
Uniprot ID
Biology Area
Vitamins / minerals,Cancer,Vitamins / Minerals
Function
Involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.
Chemical Properties
Molecular WeightTheoretical: 161 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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