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LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc)
(Synonyms: MIR10, LIR2, LILRB2, ILT4CD85d, ILT-4, ILT4, CD85d) Copy Product InfoSynonyms: MIR10, LIR2, LILRB2, ILT4CD85d, ILT-4, ILT4, CD85d
Catalog No. TMPK-01100 Copy Product Info
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 74.1 kDa and the accession number is Q8N423-1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $41 | 7-10 days | 7-10 days | |
| 10 μg | $62 | 7-10 days | 7-10 days | |
| 20 μg | $98 | 7-10 days | 7-10 days | |
| 50 μg | $188 | 7-10 days | 7-10 days | |
| 100 μg | $313 | 7-10 days | 7-10 days | |
| 200 μg | $568 | 7-10 days | 7-10 days | |
| 500 μg | $1,260 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | 1. Immobilized Human LILRB2, hFc Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-LILRB2 Antibody, hFc Tag with the EC50 of 14.6ng/ml determined by ELISA (QC Test).
2. Human LILRB2, hFc Tag captured on Protein A chip, can bind Human ANGPTL2, His Tag with an affinity constant of 0.14μM as determined in a SPR assay. |
| Description | The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 74.1 kDa and the accession number is Q8N423-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | Q8N423-1 |
| Construction | Gln22-His458 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | MIR10, LIR2, LILRB2, ILT4CD85d, ILT-4, ILT4, CD85d |
| Research Background |
| Molecular Weight | 74.1 kDa (predicted). Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result. |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc) chemical structure | LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc) molecular weight
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