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Anti-IL-17RA Antibody-APC (7E127)
🥰Excellent
Catalog No. TMAY-01300A
Anti-IL-17RA Antibody-APC (7E127) is a APC-conjugated Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody-APC (7E127) can be used in FCM.
Anti-IL-17RA Antibody-APC (7E127)
Anti-IL-17RA Antibody-APC (7E127)
🥰Excellent
Catalog No. TMAY-01300A
Anti-IL-17RA Antibody-APC (7E127) is a APC-conjugated Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody-APC (7E127) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IL-17RA Antibody-APC (7E127) is a APC-conjugated Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody-APC (7E127) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 7E127 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human IL17RA(CD217) expression on human whole blood granulocytes. Cells were stained with APC-conjugated anti-Human IL17RA(CD217). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL17RA/IL-17RA/CD217 (rh IL17RA/IL-17RA/CD217; TMPY-01371; NP_055154.3; Met1-Trp320) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails, and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans. |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human IL17RA/IL-17RA/CD217 Protein (TMPY-01371) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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