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Anti-Phospho-PKM (Ser37) Polyclonal Antibody
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Catalog No. TMAC-03352
Anti-Phospho-PKM (Ser37) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKM (Ser37). Anti-Phospho-PKM (Ser37) Polyclonal Antibody can be used in WB,IF.
Anti-Phospho-PKM (Ser37) Polyclonal Antibody
Anti-Phospho-PKM (Ser37) Polyclonal Antibody
😃Good
Catalog No. TMAC-03352
Anti-Phospho-PKM (Ser37) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKM (Ser37). Anti-Phospho-PKM (Ser37) Polyclonal Antibody can be used in WB,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $218 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
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| Description | Anti-Phospho-PKM (Ser37) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKM (Ser37). Anti-Phospho-PKM (Ser37) Polyclonal Antibody can be used in WB,IF. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. Weiwei Yang1, Yanhua Zheng1, Yan Xia1, Haitao Ji, "ERK1/2-dependent phosphorylation and nucleartranslocation of PKM2 promotes the Warburg effect." Nature Cell Biology(2012)|doi:10.1038/ncb2629 |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 37(I-D-S(p)-P-P) derived from Human PKM2 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 60 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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