PVRIG Protein, Mouse, Recombinant (hFc)

Name: PVRIG Protein, Mouse, Recombinant (hFc)
Brand: TargetMol
SKU: TMPJ-00428
Rating: 4.5 (1 reviews)

(Synonyms: transmembrane protein PVRIG, PVRIG, MGC2463, MGC138297, MGC104322, CD112R, C7orf15MGC138295, C7orf15) Copy Product Info

Synonyms: transmembrane protein PVRIG, PVRIG, MGC2463, MGC138297, MGC104322, CD112R, C7orf15MGC138295, C7orf15

Catalog No. TMPJ-00428 Copy Product Info

PVRIG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 48-55 KDa and the accession number is A0A1B0GS01.

Pack Size	Price	USA Stock	Global Stock
5 µg	$55	35 days	35 days
10 µg	$86	35 days	35 days
20 µg	$137	35 days	35 days
50 µg	$262	35 days	35 days
100 µg	$495	35 days	35 days
200 µg	$943	35 days	35 days
500 µg	$2,230	35 days	35 days
1 mg	$3,350	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	PVRIG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 48-55 KDa and the accession number is A0A1B0GS01.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	A0A1B0GS01
Amino Acid	Ser35-Asp165
Construction	Ser35-Asp165
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	transmembrane protein PVRIG, PVRIG, MGC2463, MGC138297, MGC104322, CD112R, C7orf15MGC138295, C7orf15
Research Background	PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The extracellular domain sequence of human and mouse PVRIG have approximately 65% similarity. PVRIG functions as a cell surface receptor for Nectin-2/CD112, a cell surface protein that is widely expressed on antigen-presenting cells and tumor cells. Disrupting the PVRIG/Nectin-2 interaction enhances human T cell response, suggesting PVRIG is a novel checkpoint for human T cells. PVRIG may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

Chemical Properties

Molecular Weight

48-55 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.