FLT3 Ligand Protein, Human, Recombinant

Name: FLT3 Ligand Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-06873
Price: 115 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: fms related tyrosine kinase 3 ligand, FLT3LG, FLT3L, FL) Copy Product Info

Synonyms: fms related tyrosine kinase 3 ligand, FLT3LG, FLT3L, FL

Catalog No. TMPY-06873 Copy Product Info

FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$115	-	In Stock
10 µg	$175	-	In Stock
20 µg	$265	In Stock	In Stock
50 µg	$490	7-10 days	7-10 days
100 µg	$830	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95 % as determined by SDS-PAGE.

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured in a cell proliferation assay using BaF3 mouse proB cells transfected with mouse Flt3. The ED50 for this effect is typically 1-6 ng/mL.
Description	FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P49771-1
Construction	A DNA sequence encoding the human FLT3LG (P49771-1) (Thr27-Ala181) was expressed. Predicted N terminal: Met
Protein Purity	≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC. ,
Endotoxin	< 10 EU/mg of the protein.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	fms related tyrosine kinase 3 ligand, FLT3LG, FLT3L, FL
Research Background	FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of the hematopoietic progenitors and stem cells. This may help the system to kill cancer cells. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3L controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 -positive classical DCs and their CD103 -positive tissue counterparts.

Chemical Properties

Molecular Weight

17.75 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.