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Phoenixin-14 TFA

🥰Excellent
Catalog No. T81485
Alias PNX-14 TFA

Phoenixin-14 TFA (PNX-14) is a blood-brain barrier (BBB)-penetrable neuropeptide with anxiolytic, cardioprotective, and neuroprotective properties. It modulates pituitary gonadotrophin release by enhancing gonadotropin-releasing hormone (GnRH) receptor mRNA expression and promotes insulin secretion. Additionally, PNX-14 TFA protects against ischemia/reperfusion (IR) injury in mice and combats oxidative stress by diminishing reactive oxygen species (ROS) and elevating glutathione (GSH) levels [1] [2] [3].

Phoenixin-14 TFA
Other Forms of Phoenixin-14 TFA:
Phoenixin-14T804221415039-79-0
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Phoenixin-14 TFA

🥰Excellent
Purity: 99.11%
Catalog No. T81485Alias PNX-14 TFA
Phoenixin-14 TFA (PNX-14) is a blood-brain barrier (BBB)-penetrable neuropeptide with anxiolytic, cardioprotective, and neuroprotective properties. It modulates pituitary gonadotrophin release by enhancing gonadotropin-releasing hormone (GnRH) receptor mRNA expression and promotes insulin secretion. Additionally, PNX-14 TFA protects against ischemia/reperfusion (IR) injury in mice and combats oxidative stress by diminishing reactive oxygen species (ROS) and elevating glutathione (GSH) levels [1] [2] [3].
Pack SizePriceAvailabilityQuantity
1 mg$85In Stock
5 mg$189In Stock
10 mg$284In Stock
25 mg$483In Stock
50 mg$724In Stock
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Purity:99.11%
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Product Introduction

Bioactivity
Description
Phoenixin-14 TFA (PNX-14) is a blood-brain barrier (BBB)-penetrable neuropeptide with anxiolytic, cardioprotective, and neuroprotective properties. It modulates pituitary gonadotrophin release by enhancing gonadotropin-releasing hormone (GnRH) receptor mRNA expression and promotes insulin secretion. Additionally, PNX-14 TFA protects against ischemia/reperfusion (IR) injury in mice and combats oxidative stress by diminishing reactive oxygen species (ROS) and elevating glutathione (GSH) levels [1] [2] [3].
SynonymsPNX-14 TFA
Chemical Properties
Molecular Weight1583.78 (free base)
FormulaC75H110N18O20.xC2HF3O2
Smiles[H]N[C@@H](CC(O)=O)C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N2CCC[C@H]2C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CNC4=C3C=CC=C4)C(N[C@H](C(N[C@@H](CC(O)=O)C(N5CCC[C@H]5C(N[C@@H](CC6=CC=CC=C6)C(N)=O)=O)=O)=O)CO)=O)=O)C(C)C)=O)CCCCN)=O)CC(C)C)=O)=O)=O)=O)CCC(N)=O)=O)C(C)C)=O.OC(C(F)(F)F)=O
SequenceAsp-Val-Gln-Pro-Pro-Gly-Leu-Lys-Val-Trp-Ser-Asp-Pro-Phe-NH2
Sequence ShortDVQPPGLKVWSDPF-NH2
Storage & Solubility Information
Storagekeep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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