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Bimatoprost acid
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Catalog No. T20939Cas No. 38344-08-0
Alias 17-phenyl trinor Prostaglandin F2α, 17-phenyl trinor PGF2α
Bimatoprost acid (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and has a potential antagonistic activity for the FP receptor. It has a relative potency of 756% compared to PGF2α for binding to the FP receptor on ovine luteal cells.
Bimatoprost acid
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Purity: 99.29%
Catalog No. T20939Alias 17-phenyl trinor Prostaglandin F2α, 17-phenyl trinor PGF2αCas No. 38344-08-0
Bimatoprost acid (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and has a potential antagonistic activity for the FP receptor. It has a relative potency of 756% compared to PGF2α for binding to the FP receptor on ovine luteal cells.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $135 | In Stock | In Stock | |
| 5 mg | $320 | In Stock | In Stock | |
| 10 mg | $475 | In Stock | In Stock | |
| 25 mg | $779 | In Stock | In Stock | |
| 50 mg | $1,080 | In Stock | In Stock | |
| 100 mg | $1,460 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $343 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.29%
Appearance:Viscous
Color:White
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Product Introduction
Bimatoprost acid AI Summary
Bimatoprost acid exhibits agonist activity at various human prostaglandin receptors. It shows potent agonist activity at the human prostaglandin FP receptor with an EC50 of 12.0 nM, moderate activity at the human EP3 receptor with an EC50 of 8600.0 nM, and is inactive at the human IP receptor with an EC50 greater than 10,000.0 nM..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Bimatoprost acid (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and has a potential antagonistic activity for the FP receptor. It has a relative potency of 756% compared to PGF2α for binding to the FP receptor on ovine luteal cells. |
| Synonyms | 17-phenyl trinor Prostaglandin F2α, 17-phenyl trinor PGF2α |
| Molecular Weight | 388.5 |
| Formula | C23H32O5 |
| Cas No. | 38344-08-0 |
| Smiles | C(/C=C\CCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCC2=CC=CC=C2)O)[C@H](O)C[C@@H]1O |
| Relative Density. | 1.31g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 65 mg/mL (167.31 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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