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Anti-SPARCL1 Antibody (1O104)

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Catalog No. TMAY-00162
Alias SPARC like 1, Sc1, mast9, hevin, Ecm2

Anti-SPARCL1 Antibody (1O104) is a Mouse antibody targeting SPARCL1. Anti-SPARCL1 Antibody (1O104) can be used in ELISA(Cap).

Anti-SPARCL1 Antibody (1O104)

Anti-SPARCL1 Antibody (1O104)

😃Good
Catalog No. TMAY-00162Alias SPARC like 1, Sc1, mast9, hevin, Ecm2
Anti-SPARCL1 Antibody (1O104) is a Mouse antibody targeting SPARCL1. Anti-SPARCL1 Antibody (1O104) can be used in ELISA(Cap).
Pack SizePriceAvailabilityQuantity
20 μL64 € 7-10 days
100 μL189 € 7-10 days
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Product Introduction

Bioactivity
Description
Anti-SPARCL1 Antibody (1O104) is a Mouse antibody targeting SPARCL1. Anti-SPARCL1 Antibody (1O104) can be used in ELISA(Cap).
AliasSPARC like 1, Sc1, mast9, hevin, Ecm2
Ig Type
Monoclonal Mouse IgG1
Clone
1O104
Reactivity
Human
Application
ELISA(Cap)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SPARCL1 / SPARC-like 1 (rh SPARCL1 / SPARC-like 1; NP_004675.3Met1-Phe664). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundSPARC-like protein 1 (SPARCL1; also known as SC1, high endothelial venule protein, or hevin) is an extracellular matrix-associated, secreted glycoprotein belonging to the secreted protein acidic and rich in cysteine (SPARC) family of matricellular proteins. It contains three conserved structural domains that are implicated in the regulation of cell adhesion, migration, and proliferation. SPARCL1 is expressed during embryogenesis and tissue remodeling and is especially prominent in brain and vasculature. Its down-regulation in a number of cancers and the possibility of its functional compensation by SPARC has led to recent interest in hevin as a tumor suppressor and regulator of angiogenesis. SPARCL1 has antiadhesive properties, and loss of SPARCL1 expression is associated with increased proliferative activity and cell cycle progression. It is suggested that it may influence multiple cellular processes during distinct stages of brain development and function. Besides, SPARCL1 can influence the function of astroglial cells in the developing and mature central nervous system (CNS).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human SPARCL1 / SPARC-like 1 Protein
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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