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Mal-PEG2-Val-Cit-PABA

Name: Mal-PEG2-Val-Cit-PABA
Brand: TargetMol
SKU: T77844
Price: 55 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77844Cas No. 1662687-83-3

Mal-PEG2-Val-Cit-PABA is a cleavable ADC linker, which can be used for the synthesis of ADC (antibody-drug conjugate).

Mal-PEG2-Val-Cit-PABA

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Purity: 99.72%

Catalog No. T77844Cas No. 1662687-83-3

Mal-PEG2-Val-Cit-PABA is a cleavable ADC linker, which can be used for the synthesis of ADC (antibody-drug conjugate).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$55	-	In Stock
5 mg	$129	-	In Stock
10 mg	$213	-	In Stock
25 mg	$359	-	In Stock
50 mg	$533	-	In Stock
100 mg	$759	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.72%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

Mal-PEG2-Val-Cit-PABA is a cleavable ADC linker, which can be used for the synthesis of ADC (antibody-drug conjugate).

Chemical Properties

Molecular Weight	590.63
Formula	C₂₇H₃₈N₆O₉
Cas No.	1662687-83-3
Smiles	[C@H](C(NC1=CC=C(CO)C=C1)=O)(NC([C@@H](NC(OCCOCCN2C(=O)C=CC2=O)=O)[C@@H](C)C)=O)CCCNC(N)=O
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (169.31 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6931 mL	8.4655 mL	16.9311 mL	84.6554 mL
5 mM	0.3386 mL	1.6931 mL	3.3862 mL	16.9311 mL
10 mM	0.1693 mL	0.8466 mL	1.6931 mL	8.4655 mL
20 mM	0.0847 mL	0.4233 mL	0.8466 mL	4.2328 mL
50 mM	0.0339 mL	0.1693 mL	0.3386 mL	1.6931 mL
100 mM	0.0169 mL	0.0847 mL	0.1693 mL	0.8466 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc