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N-(beta-Ketocaproyl)-L-hoMoserine lactone
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Catalog No. T22374Cas No. 143537-62-6
Alias N-(β-Ketocaproyl)-L-hoMoserine lactone, N-(Ketocaproyl)-L-homoserine lactone, N-(β-Ketocaproyl)-L-hoMoserine lactone
N-(beta-Ketocaproyl)-L-hoMoserine lactone (N-(Ketocaproyl)-L-homoserine lactone) is a component of quorum regulatory sensing and an autoinducer of P. fischeri luciferase.
N-(beta-Ketocaproyl)-L-hoMoserine lactone
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Purity: 99.76%
Catalog No. T22374Alias N-(β-Ketocaproyl)-L-hoMoserine lactone, N-(Ketocaproyl)-L-homoserine lactone, N-(β-Ketocaproyl)-L-hoMoserine lactoneCas No. 143537-62-6
N-(beta-Ketocaproyl)-L-hoMoserine lactone (N-(Ketocaproyl)-L-homoserine lactone) is a component of quorum regulatory sensing and an autoinducer of P. fischeri luciferase.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $39 | In Stock | In Stock | |
| 25 mg | $80 | In Stock | In Stock | |
| 50 mg | $139 | In Stock | In Stock | |
| 100 mg | $217 | In Stock | In Stock | |
| 200 mg | $323 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $30 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.76%
Appearance:Solid
Color:White
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Product Introduction
N-(beta-Ketocaproyl)-L-hoMoserine lactone AI Summary
N-(beta-Ketocaproyl)-L-hoMoserine lactone shows a range of activities related to bacterial quorum sensing receptors. It acts as an agonist at the Escherichia coli DH5alpha LasR receptor, with an EC50 value greater than 10000.0 nM, indicating a weak agonistic effect. Additionally, it exhibits both inhibitory and activating effects on LasR in Pseudomonas aeruginosa and Escherichia coli, with IC50 values of 40000.0 nM and 10400.0 nM, respectively, for inhibition, and an EC50 value greater than 100000.0 nM for activation in Escherichia coli JLD271. In Vibrio fischeri ES114 expressing luxI, N-(beta-Ketocaproyl)-L-hoMoserine lactone acts as an agonist in the LuxR-mediated quorum sensing system, as evidenced by increased luminescence intensity after 4 to 8 hours of incubation, with an EC50 value of 3000.0 nM. These diverse bioactivities suggest that N-(beta-Ketocaproyl)-L-hoMoserine lactone has the potential to modulate quorum sensing pathways in multiple bacterial species..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | N-(beta-Ketocaproyl)-L-hoMoserine lactone (N-(Ketocaproyl)-L-homoserine lactone) is a component of quorum regulatory sensing and an autoinducer of P. fischeri luciferase. |
| Synonyms | N-(β-Ketocaproyl)-L-hoMoserine lactone, N-(Ketocaproyl)-L-homoserine lactone, N-(β-Ketocaproyl)-L-hoMoserine lactone |
| Molecular Weight | 213.23 |
| Formula | C10H15NO4 |
| Cas No. | 143537-62-6 |
| Smiles | N(C(CC(CCC)=O)=O)[C@@H]1C(=O)OCC1 |
| Relative Density. | 1.17 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45 mg/mL (211.04 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (9.38 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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