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Ocaperidone

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Catalog No. T3497Cas No. 129029-23-8
Alias R79598, Ocaperidona

Ocaperidona (Ocaperidone (Ocaperidona)), a very high affinity dopamine D2 antagonist.

Ocaperidone

Ocaperidone

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🥰Excellent
Purity: 99.33%
Catalog No. T3497Alias R79598, OcaperidonaCas No. 129029-23-8
Ocaperidona (Ocaperidone (Ocaperidona)), a very high affinity dopamine D2 antagonist.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$39In StockIn Stock
5 mg$89In StockIn Stock
10 mg$122In StockIn Stock
25 mg$222In StockIn Stock
50 mg$372In StockIn Stock
100 mg$538In StockIn Stock
1 mL x 10 mM (in DMSO)$98In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.33%
Appearance:Solid
Color:Yellow
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Product Introduction

Ocaperidone AI Summary
Ocaperidone shows potential as a protease inhibitor against the SARS-CoV-2 virus with 22.16% inhibition of SARS-CoV-2 3CL-Pro protease at a 20 µM concentration. Additionally, it exhibits antiviral activity by inhibiting virus-induced cytotoxicity in VERO-6 cells, demonstrating 0.25% inhibition of SARS-CoV-2 induced cytotoxicity at a 10 µM concentration after 48 hours of exposure. The compound has an IC50 value greater than 20000.0 nM, indicating moderate potency in inhibiting the virus..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Ocaperidona (Ocaperidone (Ocaperidona)), a very high affinity dopamine D2 antagonist.
Targets&IC50
5-HT2:0.14 nM(Ki), 5-HT1A receptor:7.6 (pEC50, h5-HT 1A), 5-HT1A receptor:8.08 (pKi, h5-HT 1A), α1:0.46 nM (Ki), D2:0.75 nM (Ki), α2:5.4 nM (Ki), H1:1.6 nM (Ki)
SynonymsR79598, Ocaperidona
Chemical Properties
Molecular Weight420.48
FormulaC24H25FN4O2
Cas No.129029-23-8
SmilesCc1cccn2c1nc(C)c(CCN1CCC(CC1)c1noc3cc(F)ccc13)c2=O
Relative Density.1.34g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: Slightly soluble

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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