Shopping Cart

Remove All
Your shopping cart is currently empty

Proceed to checkout Continue shopping

PF-04885614

Name: PF-04885614
Brand: TargetMol
SKU: T12421
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T12421Cas No. 1480833-70-2

PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.

PF-04885614

😃Good

Catalog No. T12421Cas No. 1480833-70-2

PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.

Pack Size	Price	Availability
2 mg	$35	Backorder
5 mg	$58	Backorder
10 mg	$93	Backorder
25 mg	$178	Backorder
50 mg	$333	Backorder
100 mg	$470	Backorder
200 mg	$662	Backorder
1 mL x 10 mM (in DMSO)	$58	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Resource Download

Product Introduction

Bioactivity

Description

PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.

Chemical Properties

Molecular Weight	285.27
Formula	C₁₃H₁₄F₃N₃O
Cas No.	1480833-70-2
Smiles	CC(C)(N)c1ncc([nH]1)-c1ccc(OC(F)(F)F)cc1
Relative Density.	1.293 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 240 mg/mL (841.34 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5055 mL	17.5273 mL	35.0545 mL	175.2725 mL
5 mM	0.7011 mL	3.5055 mL	7.0109 mL	35.0545 mL
10 mM	0.3505 mL	1.7527 mL	3.5055 mL	17.5273 mL
20 mM	0.1753 mL	0.8764 mL	1.7527 mL	8.7636 mL
50 mM	0.0701 mL	0.3505 mL	0.7011 mL	3.5055 mL
100 mM	0.0351 mL	0.1753 mL	0.3505 mL	1.7527 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc