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Anti-EGF Polyclonal Antibody 3 is a Rabbit antibody targeting EGF. Anti-EGF Polyclonal Antibody 3 can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $221 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $529 | 7-10 days |
Description | Anti-EGF Polyclonal Antibody 3 is a Rabbit antibody targeting EGF. Anti-EGF Polyclonal Antibody 3 can be used in ELISA,IF,IHC-Fr,IHC-P,WB. |
Synonyms | epidermal growth factor |
Ig Type | IgG |
Reactivity | Mouse (predicted:Rat) |
Application | |
Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:50-200; ELISA: 1:5000-10000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Membrane. |
Tissue Specificity | Expressed in kidney, salivary gland, cerebrum and prostate. |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Research Background | Epidermal growth factor (EGF) is an acid- and heat-stable 53 amino acid protein originally found in rodents and humans. It has been shown to be a potent mitogen for a variety of cell types both in vivo and in vitro. EGF binds to the EGF receptor on the surface of cells and mediates intrinsic phosphorylation of the receptor on tyrosine residues. It has been detected in nearly all body fluids, such as urine (urogastrone), saliva, milk and platelet-rich plasma. EGF, TGF?and vaccinia virus growth factor exhibit 30-40% amino acid homology. Several additional members of the EGF/TGF family have been described; these include Cripto, Amphiregulin and the heparin-binding EGF-like growth factor. Amphiregulin and the heparin-binding EGF-like growth factor both bind to the EGF receptor. |
Immunogen | KLH conjugated synthetic peptide: mouse EGF |
Antigen Species | Mouse |
Gene Name | EGF |
Gene ID | |
Protein Name | Pro-epidermal growth factor |
Uniprot ID | |
Biology Area | EGF,Cell differentiation,Growth factors and hormones ELISA kits,EGF |
Function | EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. |
Molecular Weight | Theoretical: 5.8/133 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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