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H-Pro-Gly-Pro-OH

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Catalog No. T78038Cas No. 7561-51-5

H-Pro-Gly-Pro-OH, a collagen-derived matrikine, traditionally acts as a neutrophil chemoattractant, guiding these cells to target locations to orchestrate localized repair responses. Additionally, this compound initiates the transcription of neurotrophins and their receptor genes following cerebral ischemia [1] [2].

H-Pro-Gly-Pro-OH

H-Pro-Gly-Pro-OH

😃Good
Catalog No. T78038Cas No. 7561-51-5
H-Pro-Gly-Pro-OH, a collagen-derived matrikine, traditionally acts as a neutrophil chemoattractant, guiding these cells to target locations to orchestrate localized repair responses. Additionally, this compound initiates the transcription of neurotrophins and their receptor genes following cerebral ischemia [1] [2].
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Product Introduction

Bioactivity
Description
H-Pro-Gly-Pro-OH, a collagen-derived matrikine, traditionally acts as a neutrophil chemoattractant, guiding these cells to target locations to orchestrate localized repair responses. Additionally, this compound initiates the transcription of neurotrophins and their receptor genes following cerebral ischemia [1] [2].
In vivo
H-Pro-Gly-Pro-OH (37.5 µg/kg; i.p.) induces transcription of neurotrophic factors and their receptor genes after cerebral ischemia in rats [2].
Chemical Properties
Molecular Weight269.3
FormulaC12H19N3O4
Cas No.7561-51-5
SmilesC(CNC(=O)[C@@H]1CCCN1)(=O)N2[C@H](C(O)=O)CCC2
SequenceH-Pro-Gly-Pro-OH
Sequence ShortPGP
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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