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Anti-LILRA3/CD85e Antibody-PE (2I935) is a PE-conjugated Rabbit antibody targeting LILRA3/CD85e. Anti-LILRA3/CD85e Antibody-PE (2I935) can be used in FCM.
Description | Anti-LILRA3/CD85e Antibody-PE (2I935) is a PE-conjugated Rabbit antibody targeting LILRA3/CD85e. Anti-LILRA3/CD85e Antibody-PE (2I935) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 2I935 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human LILRA3(CD85e) expression on human whole blood monocytes. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with PE-conjugated anti-Human LILRA3(CD85e). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human LILRA3/CD85e/ILT6 (rh LILRA3/CD85e/ILT6; TMPY-03696; AAH28208.1; Met1-Glu439) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
Research Background | ILT6, also known as LILRA3, belongs to the ILT family. In humans, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immunoglobulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease. |
Conjucates | PE |
Others Formats | Unconjugated/FITC |
Antibody Types Available | 3 |
Immunogen | Recombinant Human LILRA3/CD85e/ILT6 Protein (TMPY-03696) |
Antigen Species | Human |
Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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