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MSLN/Mesothelin Protein, Human, Recombinant (hFc & Avi), Biotinylated

(Synonyms: SMR, MSLN, MPFSMRP, MPF, Mesothelin, CAK1) Copy Product Info

Synonyms: SMR, MSLN, MPFSMRP, MPF, Mesothelin, CAK1

Catalog No. TMPK-00959 Copy Product Info
MSLN/Mesothelin Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 61.1 kDa and the accession number is Q13421-2.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$917-10 days7-10 days
10 µg$1487-10 days7-10 days
20 µg$2457-10 days7-10 days
50 µg$4837-10 days7-10 days
100 µg$8137-10 days7-10 days
200 µg$1,4707-10 days7-10 days
500 µg$3,2507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Anti-MSLN Antibody, hFc Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human MSLN, hFc Tag with the EC50 of 18.4ng/ml determined by ELISA.
Description
MSLN/Mesothelin Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 61.1 kDa and the accession number is Q13421-2.
Species
Human
Expression System
HEK293 Cells
TagC-hFc-Avi
Accession NumberQ13421-2
ConstructionGlu296-Gly580
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsSMR, MSLN, MPFSMRP, MPF, Mesothelin, CAK1
Research Background
Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known.A knockout mouse line that lacks mesothelin reproduces and develops normally.
Chemical Properties
Molecular Weight61.1 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: MSLN/Mesothelin Protein, Human, Recombinant (hFc & Avi), Biotinylated chemical structure | MSLN/Mesothelin Protein, Human, Recombinant (hFc & Avi), Biotinylated molecular weight