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Ampicillin sodium (Domicillin) is a broad-spectrum β -lactam antibiotic. Ampicillin sodium combates a variety of Gram-positive and Gram-negative bacteria.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 g | $37 | In Stock | |
5 g | $77 | In Stock | |
10 g | $113 | In Stock | |
25 g | $187 | In Stock | |
50 g | $278 | In Stock | |
100 g | $413 | In Stock | |
1 mL x 10 mM (in DMSO) | $29 | In Stock |
Description | Ampicillin sodium (Domicillin) is a broad-spectrum β -lactam antibiotic. Ampicillin sodium combates a variety of Gram-positive and Gram-negative bacteria. |
Targets&IC50 | transporter:9.9 mM (Ki), HEK293 cells:> 100 μM (CC50), enzyme transpeptidase:1.8 µg/mL, carnitine/carnitine antiport:7.6 mM |
In vitro | METHODS: After treating porcine Escherichia coli with Ampicillin sodium (0.1, 1, 2.5, 5, 10 μg/mL), E.M.B was observed. The number of viable Escherichia coli on the culture medium. RESULTS: Ampicillin inhibited the growth of porcine Escherichia coli in a dose-dependent manner. The effective inhibitory concentration of Ampicillin is 2.5 μg/mL. [1] |
In vivo | METHODS: To study the antibacterial effect of Ampicillin sodium, Ampicillin (0.2 mL/20 g) was orally or subcutaneously injected into mice. RESULTS: The efficacy of Ampicillin in treating most infections is significantly better than that of Epicillin and Amoxycillin. [2] METHODS: To study the neuroprotective effect of Ampicillin sodium, Ampicillin sodium (200 mg/kg) was intraperitoneally injected into a mouse model of transient anterior cerebral ischemia. RESULTS: Ampicillin sodium can significantly reduce hippocampal cell death, lower the activity of matrix metalloproteinases (MMP), and increase the expression of glutamate transporter-1 (GLT-1). [3] |
Synonyms | Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, Citteral |
Molecular Weight | 371.39 |
Formula | C16H18N3NaO4S |
Cas No. | 69-52-3 |
Smiles | [Na+].CC1(C)SC2C(NC(=O)C(N)c3ccccc3)C(=O)N2C1C([O-])=O |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: 68 mg/mL (183.1 mM), Sonication is recommended. Ethanol: 69 mg/mL (185.79 mM), Sonication is recommended. DMSO: 45 mg/mL (121.17 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/H2O/Ethanol
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