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Ampicillin sodium

Name: Ampicillin sodium
Brand: TargetMol
SKU: T6386
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T6386Cas No. 69-52-3

Alias Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, Citteral

Ampicillin sodium (Domicillin) is a broad-spectrum β -lactam antibiotic. Ampicillin sodium combates a variety of Gram-positive and Gram-negative bacteria.

Ampicillin sodium

🥰Excellent

Purity: 99.26%

Catalog No. T6386Alias Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, CitteralCas No. 69-52-3

Ampicillin sodium (Domicillin) is a broad-spectrum β -lactam antibiotic. Ampicillin sodium combates a variety of Gram-positive and Gram-negative bacteria.

Pack Size	Price	USA Warehouse	Global Warehouse
1 g	$37	In Stock	In Stock
5 g	$77	-	In Stock
10 g	$113	-	In Stock
25 g	$187	-	In Stock
50 g	$278	-	In Stock
100 g	$413	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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Expected start date of shipmentUSA Warehouse [1-2 days] Global Warehouse [5-7 days]

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Batch Information

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Purity:99.26%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Ampicillin sodium (Domicillin) is a broad-spectrum β -lactam antibiotic. Ampicillin sodium combates a variety of Gram-positive and Gram-negative bacteria.
Targets&IC50	enzyme transpeptidase:1.8 µg/mL, transporter:9.9 mM (Ki), HEK293 cells:> 100 μM (CC50), carnitine/carnitine antiport:7.6 mM
In vitro	METHODS: After treating porcine Escherichia coli with Ampicillin sodium (0.1, 1, 2.5, 5, 10 μg/mL), E.M.B was observed. The number of viable Escherichia coli on the culture medium. RESULTS: Ampicillin inhibited the growth of porcine Escherichia coli in a dose-dependent manner. The effective inhibitory concentration of Ampicillin is 2.5 μg/mL. [1]
In vivo	METHODS: To study the antibacterial effect of Ampicillin sodium, Ampicillin (0.2 mL/20 g) was orally or subcutaneously injected into mice. RESULTS: The efficacy of Ampicillin in treating most infections is significantly better than that of Epicillin and Amoxycillin. [2] METHODS: To study the neuroprotective effect of Ampicillin sodium, Ampicillin sodium (200 mg/kg) was intraperitoneally injected into a mouse model of transient anterior cerebral ischemia. RESULTS: Ampicillin sodium can significantly reduce hippocampal cell death, lower the activity of matrix metalloproteinases (MMP), and increase the expression of glutamate transporter-1 (GLT-1). [3]
Synonyms	Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, Citteral

Chemical Properties

Molecular Weight	371.39
Formula	C₁₆H₁₈N₃NaO₄S
Cas No.	69-52-3
Smiles	[Na+].CC1(C)SC2C(NC(=O)C(N)c3ccccc3)C(=O)N2C1C([O-])=O
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 68 mg/mL (183.1 mM), Sonication is recommended.

Ethanol: 69 mg/mL (185.79 mM), Sonication is recommended.

DMSO: 270 mg/mL (727 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (13.46 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6926 mL	13.4629 mL	26.9259 mL	134.6294 mL
5 mM	0.5385 mL	2.6926 mL	5.3852 mL	26.9259 mL
10 mM	0.2693 mL	1.3463 mL	2.6926 mL	13.4629 mL
20 mM	0.1346 mL	0.6731 mL	1.3463 mL	6.7315 mL
50 mM	0.0539 mL	0.2693 mL	0.5385 mL	2.6926 mL
100 mM	0.0269 mL	0.1346 mL	0.2693 mL	1.3463 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc