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Ampicillin sodium

🥰Excellent
Catalog No. T6386Cas No. 69-52-3
Alias Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, Citteral

Ampicillin sodium (Domicillin) is a broad-spectrum β -lactam antibiotic. Ampicillin sodium combates a variety of Gram-positive and Gram-negative bacteria.

Ampicillin sodium

Ampicillin sodium

🥰Excellent
Purity: 99.26%
Catalog No. T6386Alias Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, CitteralCas No. 69-52-3
Ampicillin sodium (Domicillin) is a broad-spectrum β -lactam antibiotic. Ampicillin sodium combates a variety of Gram-positive and Gram-negative bacteria.
Pack SizePriceAvailabilityQuantity
1 g$37In Stock
5 g$77In Stock
10 g$113In Stock
25 g$187In Stock
50 g$278In Stock
100 g$413In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Purity:99.26%
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Product Introduction

Bioactivity
Description
Ampicillin sodium (Domicillin) is a broad-spectrum β -lactam antibiotic. Ampicillin sodium combates a variety of Gram-positive and Gram-negative bacteria.
Targets&IC50
transporter:9.9 mM (Ki), HEK293 cells:> 100 μM (CC50), enzyme transpeptidase:1.8 µg/mL, carnitine/carnitine antiport:7.6 mM
In vitro
METHODS: After treating porcine Escherichia coli with Ampicillin sodium (0.1, 1, 2.5, 5, 10 μg/mL), E.M.B was observed. The number of viable Escherichia coli on the culture medium.
RESULTS: Ampicillin inhibited the growth of porcine Escherichia coli in a dose-dependent manner. The effective inhibitory concentration of Ampicillin is 2.5 μg/mL. [1]
In vivo
METHODS: To study the antibacterial effect of Ampicillin sodium, Ampicillin (0.2 mL/20 g) was orally or subcutaneously injected into mice.
RESULTS: The efficacy of Ampicillin in treating most infections is significantly better than that of Epicillin and Amoxycillin. [2]
METHODS: To study the neuroprotective effect of Ampicillin sodium, Ampicillin sodium (200 mg/kg) was intraperitoneally injected into a mouse model of transient anterior cerebral ischemia.
RESULTS: Ampicillin sodium can significantly reduce hippocampal cell death, lower the activity of matrix metalloproteinases (MMP), and increase the expression of glutamate transporter-1 (GLT-1). [3]
SynonymsPenialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, Citteral
Chemical Properties
Molecular Weight371.39
FormulaC16H18N3NaO4S
Cas No.69-52-3
Smiles[Na+].CC1(C)SC2C(NC(=O)C(N)c3ccccc3)C(=O)N2C1C([O-])=O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 68 mg/mL (183.1 mM), Sonication is recommended.
Ethanol: 69 mg/mL (185.79 mM), Sonication is recommended.
DMSO: 45 mg/mL (121.17 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O/Ethanol
1mg5mg10mg50mg
1 mM2.6926 mL13.4629 mL26.9259 mL134.6294 mL
5 mM0.5385 mL2.6926 mL5.3852 mL26.9259 mL
10 mM0.2693 mL1.3463 mL2.6926 mL13.4629 mL
20 mM0.1346 mL0.6731 mL1.3463 mL6.7315 mL
50 mM0.0539 mL0.2693 mL0.5385 mL2.6926 mL
100 mM0.0269 mL0.1346 mL0.2693 mL1.3463 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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