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1,7-Diphenyl-4-hepten-3-one

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Catalog No. TN2522Cas No. 79559-59-4

1,7-Diphenyl-4-hepten-3-one is a compound isolated from Alpinia officinarum, which activates the Nrf2 pathway to suppress pyroptosis. It alleviates cognitive impairment and pathological damage in APP/PS1 mice and prevents oxidative stress damage while reducing levels of pyroptosis-related proteins. 1,7-Diphenyl-4-hepten-3-one enhances Aβ-induced proliferation in HT22 cells and can be used in Alzheimer’s disease research.

1,7-Diphenyl-4-hepten-3-one

1,7-Diphenyl-4-hepten-3-one

😃Good
Catalog No. TN2522Cas No. 79559-59-4
1,7-Diphenyl-4-hepten-3-one is a compound isolated from Alpinia officinarum, which activates the Nrf2 pathway to suppress pyroptosis. It alleviates cognitive impairment and pathological damage in APP/PS1 mice and prevents oxidative stress damage while reducing levels of pyroptosis-related proteins. 1,7-Diphenyl-4-hepten-3-one enhances Aβ-induced proliferation in HT22 cells and can be used in Alzheimer’s disease research.
Pack SizePriceAvailabilityQuantity
1 mg$689In Stock
5 mg$1,487Backorder
1 mL x 10 mM (in DMSO)$1,798Backorder
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Product Introduction

Bioactivity
Description
1,7-Diphenyl-4-hepten-3-one is a compound isolated from Alpinia officinarum, which activates the Nrf2 pathway to suppress pyroptosis. It alleviates cognitive impairment and pathological damage in APP/PS1 mice and prevents oxidative stress damage while reducing levels of pyroptosis-related proteins. 1,7-Diphenyl-4-hepten-3-one enhances Aβ-induced proliferation in HT22 cells and can be used in Alzheimer’s disease research.
In vitro
1,7-Diphenyl-4-hepten-3-one prevents oxidative stress damage and reduces the levels of pyrogenic proteins.
1,7-Diphenyl-4-hepten-3-one improves Aβ-induced proliferation of HT22 cells and reduces the level of pyroxy-associated proteins. [1]
In vivo
1,7-Diphenyl-4-hepten-3-one can alleviate AD-like pathology by activating Nrf2 pathway to inhibit pyrodeath. [1]
Chemical Properties
Molecular Weight264.36
FormulaC19H20O
Cas No.79559-59-4
SmilesO=C(C=CCCC=1C=CC=CC1)CCC=2C=CC=CC2
Relative Density.1.031 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Keywords

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