Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-ABCB1 Polyclonal Antibody 2

(Synonyms: Phospholipid transporter ABCB1, PGY1, P-glycoprotein 1, Multidrug resistance protein 1, MDR1, CD243, ATP-dependent translocase ABCB1, ATP-binding cassette sub-family B member 1, ABCB1) Copy Product Info
🥰Excellent

Synonyms: Phospholipid transporter ABCB1, PGY1, P-glycoprotein 1, Multidrug resistance protein 1, MDR1, CD243, ATP-dependent translocase ABCB1, ATP-binding cassette sub-family B member 1, ABCB1

Catalog No. TMAB-00022 Copy Product Info
🥰Excellent
Anti-ABCB1 Polyclonal Antibody 2 is a Rabbit antibody targeting ABCB1. Anti-ABCB1 Polyclonal Antibody 2 can be used in FCM, ICC/IF, WB.
Anti-ABCB1 Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Questions
TargetMol
View More

Product Introduction

Bioactivity
Description
Anti-ABCB1 Polyclonal Antibody 2 is a Rabbit antibody targeting ABCB1. Anti-ABCB1 Polyclonal Antibody 2 can be used in FCM, ICC/IF, WB.
SynonymsPhospholipid transporter ABCB1, PGY1, P-glycoprotein 1, Multidrug resistance protein 1, MDR1, CD243, ATP-dependent translocase ABCB1, ATP-binding cassette sub-family B member 1, ABCB1
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse)
Application
Recommended Dose
FCM=1 μg/Test; ICC/IF=1:100-500; WB=1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue SpecificityExpressed in liver, kidney, small intestine and brain.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundP Glycoprotein, the product of the MDR1 gene, is expressed in distinct non-malignant cells, typically cells with secretory and excretory functions. It is assumed to function as an ATP-dependent drug efflux pump with broad substrate specificity. The highest expression of P Glycoprotein has been observed in kidney (proximal tubules), liver (bile canaliculi), adrenal gland and intestine, suggesting that the primary role of P Glycoprotein is in the normal secretion of physiological metabolites and ingested chemicals into bile, urine and the lumen of the intestinal tract. Elevated levels of P Glycoprotein have also been reported in multidrug-resistant cell lines and in colon, endometrial, ovarian, and breast tumors, as well as in sarcomas and leukemias / lymphomas.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human MDR1
Antigen Species
Human
Gene Name
ABCB1
Gene ID
Protein Name
ATP-dependent translocase ABCB1
Uniprot ID
Biology Area
P glycoproteins,ATPases,Channels,Side Population,Surface Molecules
Function
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Subunit : Interacts with PSMB5.
Chemical Properties
Molecular WeightTheoretical: 141 kDa. Actual: 141 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Dilution Calculator
  • Reconstitution Calculator

Keywords

Related Tags: Anti-ABCB1 Polyclonal Antibody 2 molecular weight