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Anti-Ephrin A3/EFNA3 Antibody (6L127) is a Mouse antibody targeting Ephrin A3/EFNA3. Anti-Ephrin A3/EFNA3 Antibody (6L127) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
| Description | Anti-Ephrin A3/EFNA3 Antibody (6L127) is a Mouse antibody targeting Ephrin A3/EFNA3. Anti-Ephrin A3/EFNA3 Antibody (6L127) can be used in ELISA. |
| Synonyms | LERK-3, Epl3, ephrin-A3, Ehk1-L, EFL-2, AW494418 |
| Ig Type | Mouse IgG2a |
| Clone | 6L127 |
| Reactivity | Human |
| Specificity | Human Ephrin A3 |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Ephrin-A3/EFNA3 (rh Ephrin-A3/EFNA3; TMPY-01407; NP_004943.1; Met1-Ser213). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Ephrin-A3 also known as EPH-related receptor tyrosine kinase ligand 3 or EFNA3, is a member of the ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A3 and their Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: Ephrin-A3 ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. Ephrin-A3 expressed on astrocytes activates EphA4 on the post-synaptic neuron and restricts the growth of dendritic spines through multiple pathways. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Ephrin-A3/EFNA3 Protein (TMPY-01407) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |

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