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1-Naphthyl PP1 hydrochloride

Name: 1-Naphthyl PP1 hydrochloride
Brand: TargetMol
SKU: T7371
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7371Cas No. 956025-47-1

Alias 1-NA-PP 1 hydrochloride

1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of Src family kinases v-Src.

1-Naphthyl PP1 hydrochloride

😃Good

Purity: 98.63%

Catalog No. T7371Alias 1-NA-PP 1 hydrochlorideCas No. 956025-47-1

1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of Src family kinases v-Src.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$38	In Stock	In Stock
10 mg	$59	In Stock	In Stock
25 mg	$125	In Stock	In Stock
50 mg	$203	In Stock	In Stock
100 mg	$313	In Stock	In Stock
200 mg	$453	-	In Stock
1 mL x 10 mM (in DMSO)	$42	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:98.63%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of Src family kinases v-Src.
Targets&IC50	v-Src:1.0 μM , CaMK II:22 μM , CDK2:18 μM , c-Fyn:0.6 μM , c-ABL:0.6 μM
Synonyms	1-NA-PP 1 hydrochloride

Chemical Properties

Molecular Weight	353.85
Formula	C₁₉H₂₀ClN₅
Cas No.	956025-47-1
Smiles	Cl.CC(C)(C)n1nc(-c2cccc3ccccc23)c2c(N)ncnc12
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 73 mg/mL (206.3 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8261 mL	14.1303 mL	28.2606 mL	141.3028 mL
5 mM	0.5652 mL	2.8261 mL	5.6521 mL	28.2606 mL
10 mM	0.2826 mL	1.4130 mL	2.8261 mL	14.1303 mL
20 mM	0.1413 mL	0.7065 mL	1.4130 mL	7.0651 mL
50 mM	0.0565 mL	0.2826 mL	0.5652 mL	2.8261 mL
100 mM	0.0283 mL	0.1413 mL	0.2826 mL	1.4130 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc