Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin. It is a weak inhibitor of human platelet aggregation with an IC50 of 2.8 μM compared to 0.3 μM for carbaprostacyclin. 5-cis Carbaprostacyclin is a much weaker effector of rabbit mesenteric artery relaxation with an EC50 of 104 μM compared to 5.9 μM for carbaprostacyclin. It even antagonizes the adenylate cyclase activation induced by carbaprostacyclin.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 275.00 | |
1 mg | 35 days | $ 520.00 |
Description | 5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin. It is a weak inhibitor of human platelet aggregation with an IC50 of 2.8 μM compared to 0.3 μM for carbaprostacyclin. 5-cis Carbaprostacyclin is a much weaker effector of rabbit mesenteric artery relaxation with an EC50 of 104 μM compared to 5.9 μM for carbaprostacyclin. It even antagonizes the adenylate cyclase activation induced by carbaprostacyclin. |
Molecular Weight | 350.49 |
Formula | C21H34O4 |
CAS No. | 69609-77-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: >20 mg/mL (from 6B-PGI2)
DMF: >10 mg/mL (from 6B-PGI2)
DMSO: >5 mg/mL (from 6B-PGI2)
PBS (pH 7.2): >80 μg/mL (from 6B-PGI2)
You can also refer to dose conversion for different animals. More
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5-cis Carbaprostacyclin 69609-77-4 5 cis Carbaprostacyclin 5cis Carbaprostacyclin inhibitor inhibit