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Synonyms: Renal carcinoma antigen NY-REN-38, Lipopolysaccharide-associated protein 2 (LAP-2;LPS-associated protein 2), HSPCA, HSPC1, HSP90AA1, HSP90A, Heat shock protein HSP 90-alpha, Heat shock protein family C member 1, Heat shock 86 kDa (HSP 86;HSP86)

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-HSP90AA1 Antibody (5N776) is a Mouse antibody targeting HSP90AA1. Anti-HSP90AA1 Antibody (5N776) can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Renal carcinoma antigen NY-REN-38, Lipopolysaccharide-associated protein 2 (LAP-2;LPS-associated protein 2), HSPCA, HSPC1, HSP90AA1, HSP90A, Heat shock protein HSP 90-alpha, Heat shock protein family C member 1, Heat shock 86 kDa (HSP 86;HSP86) |
| Ig Type | IgG1 |
| Clone | 5N776 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Hsp90 (heat shock protein 90) is a molecular chaperone and is one of the most abundant proteins in unstressed cells. It is an ubiquitous molecular chaperone found in eubacteria and all branches of eukarya, but it is apparently absent in archaea. Whereas cytoplasmic Hsp90 is essential for viability under all conditions in eukaryotes, the bacterial homologue HtpG is dispensable under non-heat stress conditions. |
| Immunogen | KLH conjugated synthetic peptide: human Hsp90 |
| Antigen Species | Human |
| Gene Name | HSP90AA1 |
| Gene ID | |
| Protein Name | Heat shock protein HSP 90-alpha |
| Uniprot ID | |
| Biology Area | MMPs,Tumor biomarkers,Heat Shock Proteins,Organelle Proteins |
| Function | Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. |
| Molecular Weight | Theoretical: 81 kDa. Actual: 85 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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