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Anti-Phospho-KCNQ2/3/4/5 (Thr217/246/223/251) Polyclonal Antibody is a Rabbit antibody targeting Phospho-KCNQ2/3/4/5 (Thr217/246/223/251). Anti-Phospho-KCNQ2/3/4/5 (Thr217/246/223/251) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $217 | 7-10 days | |
100 μL | $318 | 7-10 days |
Description | Anti-Phospho-KCNQ2/3/4/5 (Thr217/246/223/251) Polyclonal Antibody is a Rabbit antibody targeting Phospho-KCNQ2/3/4/5 (Thr217/246/223/251). Anti-Phospho-KCNQ2/3/4/5 (Thr217/246/223/251) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA. |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Application | |
Recommended Dose | IHC-P: 1:100-300; ELISA: 1:20000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | potassium voltage-gated channel subfamily Q member 2(KCNQ2) Homo sapiens The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | 13767 |
Antigen Species | A synthesized phosphopeptide: human Kv7.3/KCNQ3 around the phosphorylation site of Thr246. AA range:191-240 |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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