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Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody
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Catalog No. TMAC-02244
Alias p-IRS1 (Ser639), p-IRS1 (S639), IRS1 (p-Ser639), IRS1 (p-S639), IRS-1, Insulin receptor substrate 1
Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IRS-1 (Ser639). Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody can be used in IHC,WB.
Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody
Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody
😃Good
Catalog No. TMAC-02244Alias p-IRS1 (Ser639), p-IRS1 (S639), IRS1 (p-Ser639), IRS1 (p-S639), IRS-1, Insulin receptor substrate 1
Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IRS-1 (Ser639). Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody can be used in IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $216 | 7-10 days | 7-10 days | |
| 100 μL | $316 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IRS-1 (Ser639). Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody can be used in IHC,WB. |
| Synonyms | p-IRS1 (Ser639), p-IRS1 (S639), IRS1 (p-Ser639), IRS1 (p-S639), IRS-1, Insulin receptor substrate 1 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extracts from 293 cells untreated or treated with serum using IRS-1 (Phospho-Ser639) Antibody TMAC-02244. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IRS-1 (Phospho-Ser639) Antibody TMAC-02244 (left) or the same antibody preincubated with blocking peptide (right).   |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 639 (P-K-S(p)-V-S) derived from Human IRS-1 |
| Antigen Species | human |
| Uniprot ID |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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