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Cell Cycle Compound Library

Catalog No. L8100
  Library Compound List   Excel SDF

Cell cycle, the ordered sequence of events that occur in a cell in preparation for cell division, is also divided into two periods: interphase and the mitotic (M) phase. Interphase itself is split into different phases: G1 phase, S phase and G2 phase. Cell Cycle related compounds rely on differing mechanisms of action to regulate the normal progression of the cell cycle. Some of these compounds interfere with CDK/cyclin complexes leaving cells stuck at the G2/M phase border, while others affect CaMKII phosphorylation, inducing arrest at the G1 phase. Other mechanisms of action include interference with RNA function and inhibition of protein synthesis. Many of these compounds ultimately induce apoptosis as a result of their interruption of the cell cycle. This library can be used for anti-cancer drug screening.

The TargetMol’s Cell Cycle Compound Library, a unique collection of 695 cell cycle related compounds, can be used for research in cell cycle and related drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
Request Library
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Product Description

  • A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Targets include CDK, ROCK, Aurora Kinase, ATM/ATR, DNA-PK, DNA/RNA Synthesis, etc.;
  • Effective tool for research in cell cycle and related diseases, such as cancer, cardiovascular diseases, inflammation, neurodegenerative diseases, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC/LCMS validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L8100)

Publications Cited TargetMol Libraries

1. Cancer Letters. 2021. 2. Cell Stem Cell. 2022 Apr 29(4) 545–558. 3. Science Bulletin. 2022. 4. Science Translational Medicine. 2022, 14(656): eabn3231. 5. Science Advances. 2023, 9(9): eade3760. 6. Nature. 2020, 582: 289-293. 7. Nature Biotechnology. 2021, 39(11): 1444-1452. 8. Nature Communications. 2022, 13(1): 1-15.. 9. Nature Communications. 2023, 14(1): 1020..
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Library Composition

DNA/RNA Synthesis (188)
CDK (143)
Apoptosis (143)
Ferroptosis (94)
Autophagy (94)
Nucleoside Antimetabolite/Analog (42)
Antibacterial (41)
Aurora Kinase (41)
Endogenous Metabolite (39)
Antibiotic (36)
DUB (33)
ROCK (31)
Serine/threonin kinase (29)
PLK (22)
Chk (19)
FLT (19)
Ras (16)
Antifolate (16)
c-Myc (15)
GSK-3 (15)
Influenza Virus (15)
Parasite (14)
Dehydrogenase (14)
PKC (14)
Src (14)
IRE1 (13)
Rho (13)
VEGFR (13)
DHFR (12)
HSV (12)
PKA (11)
Reactive Oxygen Species (11)
HIV Protease (10)
PDGFR (10)
JAK (10)
SARS-CoV (10)
PD-1/PD-L1 (10)
Nrf2 (9)
Antifungal (9)
DYRK (9)
DNA Alkylator/Crosslinker (9)
Akt (8)
FGFR (8)
Topoisomerase (8)
ERK (8)
Bcr-Abl (8)
Mitophagy (8)
NF-κB (7)
Lipoxygenase (7)
c-Kit (7)
Epigenetic Reader Domain (7)
c-RET (7)
Casein Kinase (7)
S6 Kinase (7)
APC (6)
IκB/IKK (6)
Virus Protease (6)
STAT (6)
Antioxidant (6)
PPAR (6)
MEK (5)
HMG-CoA Reductase (5)
p53 (5)
COX (5)
p38 MAPK (5)
Raf (5)
Trk receptor (5)
LIM Kinase (5)
BMI-1 (5)
EGFR (5)
Sodium Channel (4)
Proteasome (4)
SGK (4)
Tyrosine Kinases (4)
Serine Protease (4)
ROS (4)
HBV (4)
DPP-4 (4)
PI3K (4)
cell cycle arrest (4)
JNK (4)
IGF-1R (3)
LRRK2 (3)
AChR (3)
KSP (3)
Kinesin (3)
5-HT Receptor (3)
PDK (3)
DNA Methyltransferase (3)
Wnt/beta-catenin (3)
Wee1 (3)
ATPase (3)
BCL (3)
TGF-beta/Smad (3)
Calcium Channel (3)
HIF/HIF Prolyl-Hydroxylase (3)
DNA Alkylation (3)
c-Met/HGFR (3)
Drug Metabolite (3)
Reverse Transcriptase (3)
GluR (3)
Glutathione Peroxidase (3)
GPX (3)
HCV Protease (3)
Mitochondrial Metabolism (3)
ribosome (2)
Syk (2)
PYK2 (2)
TAM Receptor (2)
P450 (2)
TRP/TRPV Channel (2)
NADPH (2)
mTOR (2)
MTH1 (2)
Interleukin (2)
Histone Demethylase (2)
Arginase (2)
Caspase (2)
Haspin Kinase (2)
Histone Acetyltransferase (2)
DNA-PK (2)
GRK (2)
iGluR (2)
cholecystokinin (2)
ATM/ATR (2)
Indoleamine 2,3-Dioxygenase (IDO) (2)
Carboxypeptidase (2)
Carbonic Anhydrase (2)
KLF (2)
DNA (2)
Antifection (2)
AMPK (2)
Amino Acids and Derivatives (2)
FAK (2)
MAPK (2)
DNA gyrase (2)
CXCR (1)
Cysteine Protease (1)
RSV (1)
c-Fms (1)
Sigma receptor (1)
Sirtuin (1)
CRISPR/Cas9 (1)
MLK (1)
CaMK (1)
BTK (1)
Telomerase (1)
Beta Amyloid (1)
Tie-2 (1)
TNF (1)
TOPK (1)
Aryl Hydrocarbon Receptor (1)
Tyrosinase (1)
Antiviral (1)
UGT (1)
VDAC (1)
Adenosine Receptor (1)
Xanthine Oxidase (1)
RIP kinase (1)
GABA Receptor (1)
Dopamine Receptor (1)
PAI-1 (1)
Microtubule Associated (1)
Myosin (1)
MAO (1)
NADPH-oxidase (1)
lysosomal autophagy (1)
NMDAR (1)
NO Synthase (1)
NOD-like Receptor (NLR) (1)
IRAK (1)
OCT (1)
Opioid Receptor (1)
P2Y Receptor (1)
IL Receptor (1)
HSP (1)
Histone Methyltransferase (1)
E1/E2/E3 Enzyme (1)
Potassium Channel (1)
Free radical scavengers (1)
MNK (1)
Glucokinase (1)
Proton pump (1)
Glutathione reductase (1)
GPR (1)
GST (1)
Histamine Receptor (1)
Pim (1)
HIF (1)
Phospholipase (1)
Phosphatase (1)
P-gp (1)
PERK (1)
YAP (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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