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TargetMol | Compound Library

Cell Cycle Compound Library

Catalog No. L8100

Cell cycle, the ordered sequence of events that occur in a cell in preparation for cell division, is also divided into two periods: interphase and the mitotic (M) phase. Interphase itself is split into different phases: G1 phase, S phase and G2 phase. Cell Cycle related compounds rely on differing mechanisms of action to regulate the normal progression of the cell cycle. Some of these compounds interfere with CDK/cyclin complexes leaving cells stuck at the G2/M phase border, while others affect CaMKII phosphorylation, inducing arrest at the G1 phase. Other mechanisms of action include interference with RNA function and inhibition of protein synthesis. Many of these compounds ultimately induce apoptosis as a result of their interruption of the cell cycle. This library can be used for anti-cancer drug screening.

The TargetMol's Cell Cycle Compound Library, a unique collection of 1000 cell cycle related compounds, can be used for research in cell cycle and related drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L8100

Cell Cycle Compound Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1000 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Targets include CDK, ROCK, Aurora Kinase, ATM/ATR, DNA-PK, DNA/RNA Synthesis, etc.;
  • Effective tool for research in cell cycle and related diseases, such as cancer, cardiovascular diseases, inflammation, neurodegenerative diseases, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC/LCMS validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Targetmol Compound Libraries
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Library Customization | TargetMol Library Composition

DNA/RNA Synthesis
CDK
Apoptosis
Nucleoside Antimetabolite/Analog
Autophagy
DUB
Aurora Kinase
ROCK
Ras
Antibacterial
Endogenous Metabolite
Antibiotic
Serine/threonin kinase
GSK-3
PLK
Virus Protease
Rho
DHFR
Chk
DYRK
FLT
PD-1/PD-L1
Antifolate
Parasite
c-Myc
VEGFR
PKC
Src
PKA
HSV
HIV Protease
IRE1
Dehydrogenase
ERK
SARS-CoV
Influenza Virus
Akt
Serine Protease
JAK
PROTACs
NF-κB
Topoisomerase
Bcr-Abl
PDGFR
Wee1
Casein Kinase
S6 Kinase
Antifungal
FGFR
HCV Protease
Caspase
LIM Kinase
Epigenetic Reader Domain
c-RET
p38 MAPK
Wnt/beta-catenin
Drug Metabolite
ROS
TGF-beta/Smad
APC/C
STAT
JNK
Calcium Channel
HBV
Tyrosine Kinases
MAPK
AChR
c-Kit
BMI-1
DNA Alkylator/Crosslinker
PI3K
Adenosine Receptor
Pim
Reactive Oxygen Species
Molecular Glues
KLF
PDK
AMPK
MEK
SGK
PARP
Raf
Cell Cycle Arrest
MTH1
Lipoxygenase
EGFR
OXPHOS
LRRK2
Bcl-2 Family
mTOR
Antiviral
Trk receptor
IκB/IKK
ATM/ATR
MDM-2/p53
Nrf2
Reverse Transcriptase
Anti-infection
Sodium Channel
FAK
Kinesin
c-Met/HGFR
Histone Demethylase
Mitophagy
PYK2
Mitochondrial Metabolism
Cholecystokinin Receptor
Aryl Hydrocarbon Receptor
E1/E2/E3 Enzyme
Haspin Kinase
Antifection
KSP
Interleukin
IGF-1R
Beta Amyloid
TNF
NO Synthase
Carboxypeptidase
DNA Methyltransferase
ADC Cytotoxin
Carbonic Anhydrase
DNA-PK
Histone Methyltransferase
Arginase
MicroRNA
Ligands for Target Protein for PROTAC
YAP
AAK1
MAO
IDO
LDL
DNA gyrase
PPAR
GRK
DNA Alkylation
IL Receptor
MMP
DNA
CaMK
P-gp
HSP
Cholinesterase (ChE)
COX
Indoleamine 2,3-Dioxygenase (IDO)
Telomerase
Prostaglandin Receptor
Histone Acetyltransferase
c-Fms
5-HT Receptor
DAPK
IRAK
Retinoid Receptor
CRISPR/Cas9
GABA Receptor
Syk
TAM Receptor
Microtubule Associated
HIF/HIF Prolyl-Hydroxylase
p53
GPCR
NOS
P2Y Receptor
Reductase
BACE
Histamine Receptor
Tie-2
Glutathione Peroxidase
TOPK
ATPase
Proton pump
Dopamine Receptor
Integrin
Amino Acids and Derivatives
Ferroptosis
PERK
Necroptosis
OCT
Target Protein Ligand-Linker Conjugates
Glucokinase
TRP/TRPV Channel
Adrenergic Receptor
Myosin
RIP kinase
UGT
Endonuclease
AAK1 (AP2 associated kinase 1)
Cysteine Protease
FXR
LDLR
Adenylate cyclase
BTK
Glucosidase
Fatty Acid Synthase
CXCR
Angiotensin-converting Enzyme (ACE)
Xanthine Oxidase
GluR
glycosidase
Cytochromes P450
PANoptosis
PGE Synthase
Free radical scavengers
cGAS
PROTAC Linker
Hedgehog/Smoothened
PAK
FAAH
PTEN
Cadherin
AXL
Lipid
Huntingtin
MNK
FOXO3
ribosome
Potassium Channel
MLK
PAI-1
MELK
RSV
NOD
Tyrosinase
Liposome
NOD-like Receptor (NLR)
HER
Monoamine Oxidase
PARG(Poly(ADP-ribose) Glycohydrolase)
Poly(ADP-ribose) Glycohydrolase (PARG)
FOXO