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4-MMPB

🥰Excellent
Catalog No. T8794Cas No. 928853-86-5
Alias 15-Lipoxygenase Inhibitor 1

15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB (15-Lipoxygenase Inhibitor 1) has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxygenase-1 (15-LOX-1), respectively. 4-MMPB has potential for the research of prostate cancer.

4-MMPB

4-MMPB

🥰Excellent
Purity: 97.18%
Catalog No. T8794Alias 15-Lipoxygenase Inhibitor 1Cas No. 928853-86-5
15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB (15-Lipoxygenase Inhibitor 1) has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxygenase-1 (15-LOX-1), respectively. 4-MMPB has potential for the research of prostate cancer.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$31In StockIn Stock
5 mg$51In StockIn Stock
10 mg$83In StockIn Stock
25 mg$167In StockIn Stock
50 mg$273In StockIn Stock
100 mg$447In StockIn Stock
200 mg$632-In Stock
1 mL x 10 mM (in DMSO)$56In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:97.18%
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Product Introduction

Bioactivity
Description
15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB (15-Lipoxygenase Inhibitor 1) has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxygenase-1 (15-LOX-1), respectively. 4-MMPB has potential for the research of prostate cancer.
Targets&IC50
Others:69.6 μM
In vitro
15-Lipoxygenase Inhibitor 1 has an IC50 of 69.6 μM for DPPH bleaching；15-Lipoxygenase Inhibitor 1 (41.48 μM; 72 hours) induces apoptosis and DNA damage in PC-3 Cells[1][2].
Synonyms15-Lipoxygenase Inhibitor 1
Chemical Properties
Molecular Weight313.42
FormulaC16H19N5S
Cas No.928853-86-5
SmilesCN1CCN(CC1)c1nc(C)c2Nc3ccccc3Sc2n1
Relative Density.1.265 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 8 mg/mL (25.52 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween-80+45% Saline: 0.5 mg/mL (1.6 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1906 mL15.9530 mL31.9061 mL159.5303 mL
5 mM0.6381 mL3.1906 mL6.3812 mL31.9061 mL
10 mM0.3191 mL1.5953 mL3.1906 mL15.9530 mL
20 mM0.1595 mL0.7977 mL1.5953 mL7.9765 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

scavengingradicalLOXLipoxygenaseInhibitorinhibitioninhibitcancerApoptosis4-MMPB4MMPB4 MMPB
Related Tags: buy 4-MMPB | purchase 4-MMPB | 4-MMPB cost | order 4-MMPB | 4-MMPB chemical structure | 4-MMPB in vitro | 4-MMPB formula | 4-MMPB molecular weight
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