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LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
(Synonyms: LRRC15, LIB, EGM_11224) Copy Product InfoSynonyms: LRRC15, LIB, EGM_11224
Catalog No. TMPK-01380 Copy Product Info
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 58.92 kDa and the accession number is A0A2K5UKB6.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $58 | - | In Stock | |
| 10 µg | $92 | - | In Stock | |
| 20 µg | $148 | 7-10 days | 7-10 days | |
| 50 µg | $289 | 7-10 days | 7-10 days | |
| 100 µg | $487 | 7-10 days | 7-10 days | |
| 200 µg | $883 | 7-10 days | 7-10 days | |
| 500 µg | $1,950 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95% as determined by Tris-Bis PAGE
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Anti-LRRC15 Antibody, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Cynomolgus LRRC15, His Tag with the EC50 of 26.5ng/ml determined by ELISA. |
| Description | The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 58.92 kDa and the accession number is A0A2K5UKB6. |
| Species | Cynomolgus,Rhesus |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | A0A2K5UKB6/F7FSB9 |
| Construction | Tyr22-Gly538 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | LRRC15, LIB, EGM_11224 |
| Research Background | The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. |
| Molecular Weight | 58.92 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) chemical structure | LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) molecular weight
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