Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PC DBCO-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Description | PC DBCO-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | PC DBCO-PEG4-NHS ester |
Molecular Weight | 945.976 |
Formula | C47H55N5O16 |
CAS No. | 2055025-02-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PC DBCO-PEG4-NHS ester 2055025-02-8 PC DBCO PEG4 NHS ester PC DBCO-PEG-4-NHS ester PC DBCOPEG4NHS ester inhibitor inhibit